conantokin R
conantokin R Basic information
- Product Name:
- conantokin R
- Synonyms:
-
- conantokin R
- PubChem ID: 90488802
- L-Proline, glycyl-L-α-glutamyl-4-carboxy-L-α-glutamyl-4-carboxy-L-α-glutamyl-L-valyl-L-alanyl-L-lysyl-L-methionyl-L-alanyl-L-alanyl-4-carboxy-L-α-glutamyl-L-leucyl-L-alanyl-L-arginyl-4-carboxy-L-α-glutamyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-lysylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-asparaginyl-L-c...
- L-Proline, glycyl-L-α-glutamyl-4-carboxy-L-α-glutamyl-4-carboxy-L-α-glutamyl-L-valyl-L-alanyl-L-lysyl-L-methionyl-L-alanyl-L-alanyl-4-carboxy-L-α-glutamyl-L-leucyl-L-alanyl-L-arginyl-4-carboxy-L-α-glutamyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-lysylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-asparaginyl-L-cysteinyl-L-tyrosyl-, cyclic (21→25)-disulfide
- CAS:
- 202925-60-8
- MF:
- C127H201N35O49S3
- MW:
- 3098.36
- Mol File:
- 202925-60-8.mol
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conantokin R Chemical Properties
- Density
- 1.56±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
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conantokin R Usage And Synthesis
Description
Potent, non-competitive NMDA receptor antagonist (IC50= 93 nM) that has been suggested to have NR2 subunit selectivity. Inhibits inward currents evoked by NMDA in central nervous system neurons (IC50= 350 nM) and exhibits broad anticonvulsant and antiparkinsonian activityin vivoat doses devoid of behavioral toxicity.
conantokin RSupplier
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