1-methyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties

Boiling point:

119℃/18mm

Density 

0.966±0.06 g/cm3(Predicted)

RTECS 

NX5087850

refractive index 

1.5570 to 1.5610

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

Liquid

pka

9.73±0.40(Predicted)

color 

Pale yellow

Water Solubility 

Slightly soluble in water.

CAS DataBase Reference

4965-09-7

Safety Information

HS Code 

2933499090

1-methyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis

Chemical Properties

Colorless to pale yellow liquid

Uses

1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous antidepressant and parkinsonism-preventing substance that demonstrates neuroprotectiveactivity. Following systemic administration in rats, 1-Methyl-1,2,3,4-tetrahydroisoquinoline produces antidepressant-like effect similar to the effect of imipramine. 1MeTIQ is a reversible short-acting moderate inhibitor of MAO A/B. Also known as 1,2,3,4-Tetrahydro-1-methylisoquinoline, 1MeTIQ. It is an important raw material and intermediate for revaprazan and pharmaceutical.

Definition

ChEBI: 1-methyl-1,2,3,4-tetrahydroisoquinoline is a member of isoquinolines.

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