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Tosufloxacin tosylate

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Tosufloxacin tosylate Basic information

Product Name:
Tosufloxacin tosylate
Synonyms:
  • TOSUFLOXACIN TOSYLATE
  • 1,8-naphthyridine-3-carboxylicacid,7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluoro
  • 4-dihydro-4-oxo-phenyl)-6-fluoro-mono(4-methylbenzenesulfonate)
  • a64730
  • t3262
  • 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, mono(4-methylbenzenesulfonate) (9CI)
  • Tosuxacin
  • 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate
CAS:
115964-29-9
MF:
C26H23F3N4O6S
MW:
576.55
Product Categories:
  • Biochemistry
  • Quinolones (Antibiotics for Research and Experimental Use)
  • Antibiotics for Research and Experimental Use
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
115964-29-9.mol
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Tosufloxacin tosylate Chemical Properties

Melting point:
251-252°C
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
color 
White to Pale Yellow
BRN 
7617816
CAS DataBase Reference
115964-29-9
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
QN2791000
HS Code 
29339900
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Tosufloxacin tosylate Usage And Synthesis

Description

Tosufloxacin tosylate is a new fluoroquinolone antibacterial structurally related to temafloxacin. Mechanistically, it is a microbial DNA topoisomerase inhibitor, useful against beta-lactamase producing organisms. Tosufloxacin tosylate is reported to be particularly effective against Salmonella enteritidis.

Chemical Properties

White to Off-White Solid

Originator

Toyama (Japan)

Uses

Useful as a therapeutic antimicrobial for the treatment of respiratory infections.

Definition

ChEBI: Tosufloxacin tosylate is a racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate. It has a role as an antimicrobial agent, an antiinfective agent, a DNA synthesis inhibitor, a hepatotoxic agent and a topoisomerase IV inhibitor. It contains a tosufloxacin(1+), a (S)-tosufloxacin tosylate and a (R)-tosufloxacin tosylate.

brand name

Ozex; Tosuxacin

Tosufloxacin tosylateSupplier

Chifeng Wedge Pharmaceutical Co., Ltd. Gold
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