Basic information Safety Supplier Related

2-(1H-Indol-2-yl)aniline

Basic information Safety Supplier Related

2-(1H-Indol-2-yl)aniline Basic information

Product Name:
2-(1H-Indol-2-yl)aniline
Synonyms:
  • 2-(2'-AMINOPHENYL)INDOLE
  • 2-(2-AMINOPHENYL)INDOLE
  • 2-(2-Aminophenyl)indole 97%
  • 2-(1H-indol-2-yl)-Benzenamine
  • Benzenamine, 2-(1H-indol-2-yl)-
  • 2-(1H-indol-2-yl)aniline
CAS:
32566-01-1
MF:
C14H12N2
MW:
208.26
Product Categories:
  • Intermediates of Dyes and Pigments
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
Mol File:
32566-01-1.mol
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2-(1H-Indol-2-yl)aniline Chemical Properties

Melting point:
154-155 °C(lit.)
Boiling point:
437.9±20.0 °C(Predicted)
Density 
1.229±0.06 g/cm3(Predicted)
pka
16.53±0.30(Predicted)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3

MSDS

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2-(1H-Indol-2-yl)aniline Usage And Synthesis

Uses

Reactant in:

  • cascade reactions of benzopyranylidenemalonates with mono- and dinucleophiles

Reactant for preparation of:
  • Mono-, bis-indolo[1,2-c]quinazolines as antimicrobial agents
  • Isocryptolepine alkaloid with antimalarial activity
  • Cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines as antitumor agents

General Description

2-(2-Aminophenyl)indole is an indole derivative. It has been reported as an amination reagent. 2-(2-Aminophenyl)indole undergoes condensation with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) to afford new 6-cyanoindolo[3,2-c]quinoline derivatives, having pharmacological applications.

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