N-Trans-Feruloyltyramine CAS#: 66648-43-9

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N-Trans-Feruloyltyramine

Basic information Safety Supplier Related

N-Trans-Feruloyltyramine Basic information

Product Name:

N-Trans-Feruloyltyramine

Synonyms:

N-Trans-Feruloyltyramine
(E)-3-(4-hydroxy-3-Methoxy-phenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enaMide
2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)-
Moupinamide >=95% (LC/MS-ELSD)
(2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide
N-trans-Feruloy-Tyramine
COX,Cyclooxygenase,Inhibitor,N trans Feruloyltyramine,NtransFeruloyltyramine,inhibit
Moupimide

CAS:

66648-43-9

MF:

C18H19NO4

MW:

313.35

Mol File:

66648-43-9.mol

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N-Trans-Feruloyltyramine Chemical Properties

Melting point:: 138-140 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point:: 603.3±55.0 °C(Predicted)
Density: 1.248±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO and methan
form: powder
pka: 9.83±0.31(Predicted)
color: White
InChIKey: NPNNKDMSXVRADT-WEVVVXLNSA-N

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Safety Information

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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N-Trans-Feruloyltyramine Usage And Synthesis

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Solanaceae plant Solanum torvum, which is used as a medicine with its roots; Physalis alkekengi L. var.francheti (Mast.) Makino , its dried perennial calyx or perennial calyx with fruit as a traditional Chinese medicine is included in various editions of Chinese pharmacopoeia. .

Uses

Alfrutamide is a phenolic amides found in garlic and cocoa. Alfrutamide inhibits cyclooxygenases 1 and 2.

Definition

ChEBI: N-feruloyltyramine is a member of tyramines. It has a role as a metabolite.

Biological Activity

N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid isolated from Piper nigru, is an inhibitor of COX1 and COX2 with antioxidant and anti-inflammatory activities.

target

COX-1

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COX-2

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