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N-Trans-Feruloyltyramine

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N-Trans-Feruloyltyramine Basic information

Product Name:
N-Trans-Feruloyltyramine
Synonyms:
  • N-Trans-Feruloyltyramine
  • (E)-3-(4-hydroxy-3-Methoxy-phenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enaMide
  • 2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)-
  • Moupinamide >=95% (LC/MS-ELSD)
  • (2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide
  • N-trans-Feruloy-Tyramine
  • COX,Cyclooxygenase,Inhibitor,N trans Feruloyltyramine,NtransFeruloyltyramine,inhibit
  • Moupimide
CAS:
66648-43-9
MF:
C18H19NO4
MW:
313.35
Mol File:
66648-43-9.mol
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N-Trans-Feruloyltyramine Chemical Properties

Melting point:
138-140 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point:
603.3±55.0 °C(Predicted)
Density 
1.248±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO and methan
form 
powder
pka
9.83±0.31(Predicted)
color 
White
InChIKey
NPNNKDMSXVRADT-WEVVVXLNSA-N
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Safety Information

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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N-Trans-Feruloyltyramine Usage And Synthesis

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Solanaceae plant Solanum torvum, which is used as a medicine with its roots; Physalis alkekengi L. var.francheti (Mast.) Makino , its dried perennial calyx or perennial calyx with fruit as a traditional Chinese medicine is included in various editions of Chinese pharmacopoeia. .

Uses

Alfrutamide is a phenolic amides found in garlic and cocoa. Alfrutamide inhibits cyclooxygenases 1 and 2.

Definition

ChEBI: N-feruloyltyramine is a member of tyramines. It has a role as a metabolite.

Biological Activity

N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid isolated from Piper nigru, is an inhibitor of COX1 and COX2 with antioxidant and anti-inflammatory activities.

target

COX-1

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COX-2

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