(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Basic information
- Product Name:
- (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
- Synonyms:
-
- BenzeneMethanol,2,6-dichloro-3-fluoro-a-Methyl-, (aS)-
- (1S)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
- (S)-1-(2,6-dichloro-4-fluorophenyl)ethanol
- (1S)-1-(2,6-Dichloro-3-fluorophenyl)ethane-1-ol
- (aS)-2,6-Dichloro-3-fluoro-a-methyl-benzenemethanol
- -1-(2,6-Dichloro-3-fluorophenyl)
- (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
- (S)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
- CAS:
- 877397-65-4
- MF:
- C8H7Cl2FO
- MW:
- 209.04
- EINECS:
- 700-699-9
- Product Categories:
-
- Aromatic Ring
- Chiral Compounds
- Mol File:
- 877397-65-4.mol
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Chemical Properties
- Boiling point:
- 261.3±35.0 °C(Predicted)
- Density
- 1.406±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 13.30±0.20(Predicted)
- form
- Solid
- color
- White
- InChI
- InChI=1/C8H7Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-4,12H,1H3/t4-/s3
- InChIKey
- JAOYKRSASYNDGH-UFLUHPNLNA-N
- SMILES
- [C@H](C1C(=CC=C(F)C=1Cl)Cl)(O)C |&1:0,r|
- CAS DataBase Reference
- 877397-65-4
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Usage And Synthesis
Uses
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor ( c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
Uses
(S) -1- (2,6-dichloro-3-fluorophenyl) ethanol(C8H7C12FO) is synthesized (R)-3-[l-(2, 6-dichloro-3-fluoro-benzene)- The key intermediate of ethoxy-5- (l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -pyrimidine-2-indane. And (R)-3-[l-(2,6-dichloro-3-fluoro-benzene)-ethoxy-5-(l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -Pyrimidine-2-indane is a small molecule kinase inhibitor for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) positive for anaplastic lymphohematokinase (ALK).
Uses
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanolSupplier
- Tel
- 0571-86828652 19967494293
- sales@chemtrue-bio.com
- Tel
- 021-68187180-819 13681683526
- lchen@syncozymes.com
- Tel
- 15951285981
- huiruisales@163.com
- Tel
- 152-6236-2504 18019700392
- clong008@163.com
- Tel
- 0531-88259693 17854196142
- 2820602043@qq.com
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol(877397-65-4)Related Product Information
- Phenethyl alcohol
- 2-Methoxyethanol
- 2,2,2-TRIFLUOROETHANOL-D3
- Dichlorofluoroethane
- Ethanol
- 2-AMINO-1-PHENYLETHANOL
- Dichlorodiphenylsilane
- Ethyl acetate
- Perfluoroalkyl alcohol
- Dichloromethylphenylsilane
- (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
- 4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester
- Crizotinib
- (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine
- 1-(2,6-DICHLOROPHENYL)ETHANOL
- Dichlorodifluoromethane
- (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
- 1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHANOL