3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE Chemical Properties

Melting point:

<0°C

Boiling point:

44-45 °C2 mm Hg(lit.)

Density 

1.17 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.483(lit.)

Flash point:

145 °F

storage temp. 

2-8°C

solubility 

Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Oil

color 

Colourless to Pale Yellow

Specific Gravity

1.351

Water Solubility 

Immiscible with water.

Hydrolytic Sensitivity

4: no reaction with water under neutral conditions

BRN 

2037650

Stability:

Hygroscopic

InChIKey

GAPRPFRDVCCCHR-UHFFFAOYSA-N

CAS DataBase Reference

38002-45-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-28-36/37/39

RIDADR 

UN 3334

WGK Germany 

3

F 

8-9-19

TSCA 

No

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich

3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE Usage And Synthesis

Chemical Properties

Clear colorless to pale yellow liquid

Uses

3-Bromo-1-(trimethylsilyl)-1-propyne may be used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It may be used as reagent for the alkylation of dianion of β-keto esters at γ-carbon. It may be employed in the preparation of terminal conjugated enynes and allenic alcohols.

General Description

3-Bromo-1-(trimethylsilyl)-1-propyne is reported as a propargylating agent. Selective reaction of 3-bromo-1-(trimethylsilyl)-1-propyne with α-keto ester using indium metal has been studied.

3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE(38002-45-8)Related Product Information

• 1-TRIMETHYLSILYLMETHANOL
• 4-PHENYL-3-BUTYN-2-ONE
• 3-Bromopropyne
• 1-(Trimethylsilyl)-1-propyne
• Propyne
• 3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE
• 3-BROMO-1-(TRIETHYLSILYL)-1-PROPYNE
• 3-BROMO-1-(TRIISOPROPYLSILYL)-1-PROPYNE
• 3-BROMO-1-(TERT-BUTYLDIMETHYLSILYL)-1-PROPYNE