Basic information Safety Supplier Related

THROMBOXANE B2

Basic information Safety Supplier Related

THROMBOXANE B2 Basic information

Product Name:
THROMBOXANE B2
Synonyms:
  • THROMBOXANE B2
  • 9ALPHA,11,15S-TRIHYDROXYTHROMBA-5Z,13E-DIEN-1-OIC ACID
  • TXB2
  • [5Z,9ALPHA,11RS,13E,15S]-9,11,15-TRIHYDROXYTHROMBOXA-5,13-DIEN-1-OIC ACID
  • (5z,9α,11rs,13e,15s)-9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid
  • (E)-7-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid
  • TXB2, (5Z,9α,11RS,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid
  • (5Z,13E,15S)-9α,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid
CAS:
54397-85-2
MF:
C20H34O6
MW:
370.48
Product Categories:
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
54397-85-2.mol
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THROMBOXANE B2 Chemical Properties

Melting point:
95-96°
alpha 
D25 +57.4° (c = 0.26 in ethyl acetate)
storage temp. 
−20°C
solubility 
Chloroform (Slightly, Heated)
form 
Solid
color 
White to Off-White
Merck 
13,9466
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Safety Information

Hazard Codes 
Xn,T
Risk Statements 
63-52/53-34-32-23/24/25-5
Safety Statements 
22-36-45-36/37/39-26
WGK Germany 
3
F 
8-10-21
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THROMBOXANE B2 Usage And Synthesis

Chemical Properties

White Solid

Uses

An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

Uses

TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

Definition

ChEBI: A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.

THROMBOXANE B2Supplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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BOC Sciences
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1-631-485-4226; 16314854226
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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18521735133 18521732826;
Email
market@aladdin-e.com
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THROMBOXANE B2(54397-85-2)Related Product Information