THROMBOXANE B2 Chemical Properties

Melting point:

95-96°

alpha 

D25 +57.4° (c = 0.26 in ethyl acetate)

storage temp. 

−20°C

solubility 

Chloroform (Slightly, Heated)

form 

Solid

color 

White to Off-White

Merck 

13,9466

Safety Information

Hazard Codes 

Xn,T

Risk Statements 

63-52/53-34-32-23/24/25-5

Safety Statements 

22-36-45-36/37/39-26

WGK Germany 

3

F 

8-10-21

THROMBOXANE B2 Usage And Synthesis

Chemical Properties

White Solid

Uses

An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 (D230555) and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

Uses

TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

Definition

ChEBI: A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.

THROMBOXANE B2(54397-85-2)Related Product Information

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• Thrombospondin 2 (4)
• THROMBOXANE B3
• Thrombospondin-1 (D7E5F) Rabbit mAb
• Thrombospondin 1 (A6.1)
• Thrombospondin 4 (G-10)
• THROMBOXANE SYNTHASE BLOCKING PEPTIDE
• THROMBOXANE B2-D4
• THROMBOXANE B2
• 3-HEXENE-2,5-DIOL
• 11-DEHYDRO THROMBOXANE B2-D4
• 11-DEHYDRO THROMBOXANE B2
• PINANE THROMBOXANE A2,pinane thromboxane A2 ethanol solution
• (+/-)CARBOCYCLIC THROMBOXANE,CARBOCYCLIC THROMBOXANE A2
• THROMBOXANE B1
• Thromboxane-A Synthase
• 11-DEHYDRO THROMBOXANE B3
• THROMBOXANE A2