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3-Amino-5-bromobenzotrifluoride

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3-Amino-5-bromobenzotrifluoride Basic information

Product Name:
3-Amino-5-bromobenzotrifluoride
Synonyms:
  • BenzenaMine,3-broMo-5-(trifluoroMethyl)-
  • 3-Bromo-5-(trifluoromethyl)aniline, 5-Bromo-alpha,alpha,alpha-trifluoro-m-toluidine
  • 3-AMino-5-broMobenzotrifluoride[3-BroMo-5-(trifluoroMethyl)aniline]
  • 3-amino-5-bromotrifluorotoluene
  • 5-amino-3-bromo-trifluoromethylbenzene / 3-bromo-5-trifluoromethylaniline
  • 3-BROMO-5-TRIFLUOROMETHYL-PHENYLAMINE
  • 3-BROMO-5-(TRIFLUOROMETHYL)ANILINE
  • 3-AMINO-5-BROMO(TRIFLUOROMETHYL)BENZENE
CAS:
54962-75-3
MF:
C7H5BrF3N
MW:
240.02
EINECS:
259-412-6
Product Categories:
  • Building Blocks
  • Chemical Synthesis
  • C7
  • Nitrogen Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
  • Amines
  • blocks
  • Bromides
  • Benzotrifluoride Series
  • bc0001
Mol File:
54962-75-3.mol
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3-Amino-5-bromobenzotrifluoride Chemical Properties

Boiling point:
220-223 °C (lit.)
Density 
1.697 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.528(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
2.30±0.10(Predicted)
form 
Liquid
color 
Colorless to yellow
InChIKey
HJTLKVYOWNTDPF-UHFFFAOYSA-N
CAS DataBase Reference
54962-75-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
HS Code 
29214300

MSDS

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3-Amino-5-bromobenzotrifluoride Usage And Synthesis

Description

3-Amino-5-bromobenzotrifluoride is an organic synthetic reagent or pharmaceutical intermediate component used in the synthesis of other organic compounds such as 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, fluorinated 2-benzylphthalazine-1 (2H)-one, 1-phthalazinamine and 1-alkoxy/benzyloxyphthalazine derivatives. It can also be used to prepare the targeted anti-cancer drug Nilotinib, which can be used to treat chronic granulocytic leukaemia (CML).

Chemical Properties

White solid

Uses

3-Amino-5-bromobenzotrifluoride may be used in the synthesis of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline.

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