FMOC-5-AMINOPENTANOIC ACID Chemical Properties

Melting point:

135-136 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))

Boiling point:

575.8±33.0 °C(Predicted)

Density 

1.232±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

form 

Powder

pka

4.71±0.10(Predicted)

color 

White

BRN 

3565625

CAS DataBase Reference

123622-48-0

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich

FMOC-5-AMINOPENTANOIC ACID Usage And Synthesis

Description

Fmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

5-(Fmoc-amino)valeric acid is used as pharmaceutical intermediate.

Uses

Fmoc-5-aminopentanoic acid, tech grade

FMOC-5-AMINOPENTANOIC ACID(123622-48-0)Related Product Information

• Fmoc-D-proline
• (S)-N-Fmoc-4-Bromophenylalanine
• Fmoc-D-4-Hydroxyphenylglycine
• FMOC-2-NAL-OH
• Fmoc-5-chloro-L-tryptophan
• (S)-N-Fmoc-(3-Pyridyl)alanine
• FMOC-T-BUTYL-L-ALANINE
• Fmoc-D-Asn(Trt)-OH
• Fmoc-D-phenylalanine
• Nalpha-FMOC-L-Glutamine
• Fmoc-L-aspartic acid
• Fmoc-D-Tyr(tBu)-OH
• FMOC-D-Lys(BOC)-OH
• Fmoc-L-Cysteine
• Nalpha-FMOC-L-Asparagine
• Teneligliptin Hydrobromide Hydrate
• N-Fmoc-S-trityl-D-cysteine
• N-Fmoc-N'-trityl-D-glutamine