3-PHENYL-4-PICOLINE Chemical Properties

storage temp. 

Sealed in dry,Room Temperature

Appearance

Colorless to light yellow Liquid

3-PHENYL-4-PICOLINE Usage And Synthesis

Synthesis

Pd Catalyst 1 (12.6 mg, 0.045 mmol, calculated based on the molar concentration of Pd) and 3-chloro-4-methylpyridine (0.2 mmol) were added to a Schlenk tube equipped with a magnetic stir bar. Anhydrous toluene (2.0 mL) and phenylmagnesium bromide (0.3 mmol, 1.5 equiv) were added sequentially under nitrogen protection. The reaction mixture was heated to 140 °C and the reaction was stirred at this temperature until complete consumption of 3-chloro-4-methylpyridine was confirmed by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, the reaction mixture was purified by silica gel column chromatography to afford the target product 3-phenyl-4-methylpyridine.

References

[1] Tetrahedron, 2016, vol. 72, # 1, p. 69 - 75

3-PHENYL-4-PICOLINE(19352-29-5)Related Product Information

• 3-(3-Aminophenyl)-4-pyridinecarboxylicacidethylester
• 3-PHENYL-4-PICOLINE
• 3-(2-Methylphenyl)-4-pyridinecarboxylicacid
• 2,3,4-TRIPHENYLPYRIDINE
• 3-PHENYLISONICOTINIC ACID
• 3-PHENYLQUINOLINE-2,4-DICARBOXYLIC ACID
• 3-PHENYL-1-(PYRIDIN-2-YL)-5H-INDENO[1,2-C]PYRIDINE
• 3,4-DIPHENYLPYRIDINE
• 3-(3-Nitrophenyl)-4-pyridinecarboxylicacidmethylester
• 3-(2-Methylphenyl)-4-pyridinecarboxylicacidmethylester
• 2-ISOBUTOXY-4,6-DIMETHYL-3-[(2-METHYLPHENYL)SULFONYL]-5-PHENYLPYRIDINE
• 3-(3-Nitrophenyl)-4-pyridinecarboxylicacidethylester
• 3-(3-Aminophenyl)-4-pyridinecarboxylicacidmethylester
• AURORA KA-4886
• AKOS B001478
• AURORA KA-3900
• RARECHEM BA KZ 0039
• 2-CHLORO-4,6-DIMETHYL-3-[(2-METHYLPHENYL)SULFONYL]-5-PHENYLPYRIDINE