Dodecyl gallate Chemical Properties

Melting point:

94-97 °C (lit.)

Boiling point:

394.57°C (rough estimate)

Density 

1.0677 (rough estimate)

refractive index 

1.6120 (estimate)

storage temp. 

Store below +30°C.

solubility 

Very slightly soluble or practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride.

pka

7.93±0.25(Predicted)

color 

White to Almost white

Odor

at 100.00?%. odorless

Water Solubility 

practically insoluble

Sensitive 

Air Sensitive

BRN 

2701981

InChIKey

RPWFJAMTCNSJKK-UHFFFAOYSA-N

LogP

6.365 (est)

CAS DataBase Reference

1166-52-5(CAS DataBase Reference)

NIST Chemistry Reference

Gallic acid, n-dodecyl ester(1166-52-5)

EPA Substance Registry System

Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester (1166-52-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

43

Safety Statements 

24-37

RIDADR 

3335

WGK Germany 

1

RTECS 

DH9100000

TSCA 

Yes

HS Code 

29182950

Toxicity

LD50 orally in Rabbit: 5000 mg/kg

MSDS

• Language:English Provider:Dodecyl 3,4,5-trihydroxybenzoate
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Dodecyl gallate Usage And Synthesis

Description

This gallate ester (E 310) is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases have been reported in workers in the food industry, gallate being contained in margarine. It is also present in washing powder.

Chemical Properties

white to cream powder

Uses

Dodecyl Gallate is an antioxidant used in cream cheese, instant mashed potatoes, margarine, fats, and oils.

Uses

Dodecyl gallate is an antioxidant in cosmetic and pharmaceutical creams and emulsions, various fats, oils, waxes, and foods, such as margarine.

Uses

Dodecyl 3,4,5-Trihydroxybenzoate is used in method for stabilizing the pH of an aqueous compound comprising drug.

Definition

ChEBI: Dodecyl gallate is a gallate ester.

General Description

Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers.

Contact allergens

This gallic acid ester (E 310) is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were reported in workers of the food industry, gallate being contained in margarine, and from washing powder.

Safety Profile

Poison by ingestion and inhalation. Moderately toxic by skin contact. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. A pesticide. When heated to decomposition it emits very toxic fumes of NOx.

Carcinogenicity

In a 2-year feeding study, with the administration of up to 5 mg/kg of feed to rats, no increase in tumor incidence was noted . In female mice, a dermal injection of dodecyl gallate (100 nmol in 0.2mL acetone) inhibits the formation of skin carcinomas and papillomas induced by the tumor promoter phorbol myristate and the initiator 7,12-dimethylbenz[a]anthracene .

Dodecyl gallate (1166-52-5)Related Product Information

• MONOLAURIN
• Butylparaben
• Gallic acid
• Salicylic acid
• 3-Hydroxybenzoic acid
• SODIUM LAURETH SULFATE
• 2'-Hydroxy-3-phenylpropiophenone
• Dilauryl thiodipropionate
• 4-Hydroxybenzoic acid
• Propyl gallate
• Benzyl benzoate
• 1-Dodecanol
• Gallic acid monohydrate
• Dodecyl 2-methylacrylate
• 3,5-Dihydroxybenzoic acid
• Hexadecyl 3,4,5-trihydroxybenzoate
• Octadecyl gallate
• Erythorbic Acid