2-Pyridinol-1-oxide Chemical Properties

Melting point:

147-152 °C

Boiling point:

387.7±15.0 °C(Predicted)

Density 

1.111

vapor pressure 

0.223Pa at 25℃

Flash point:

100 °C

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

pka

pK1:-0.62;pK2:5.97(0) (25°C)

color 

Off-White to Light Yellow

Water Solubility 

331g/L

BRN 

1422545

InChIKey

JVHZMYAXZUIZKS-UHFFFAOYSA-N

LogP

-1.07 at 25℃

CAS DataBase Reference

13161-30-3(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyridinol-1-oxide(13161-30-3)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-40

Safety Statements 

26-36-22

WGK Germany 

3

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich

2-Pyridinol-1-oxide Usage And Synthesis

Chemical Properties

Weight 20% solution in water

Uses

2-Pyridinol 1-oxide can be used:

• To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.
• To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
• In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.

Definition

Bactericidal agent related to aspergillic acid, made from pyridine-N-oxide.

General Description

2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.

References

[1] Laura Cruickshank. “Rare Elements Electrochemistry: The Development of a Novel Electrochemical Sensor for the Rapid Detection of Europium in Environmental Samples Using Gold Electrode Modified with 2-pyridinol-1-oxide.” Analytical Sciences 31 7 (2015): 623–627.

2-Pyridinol-1-oxide(13161-30-3)Related Product Information

• Hydroxy silicone oil
• ETHYLENE OXIDE
• Cuprous oxide
• Sulfasalazine
• 2-Chloro-5-chloromethylpyridine
• Chromium picolinate
• 2,5-Dimethylpyridine
• 2-Hydroxypyridine
• NITRIC OXIDE
• Magnesium oxide
• Iron oxide
• PYRIDINE-D5
• Pyridine-N-oxide
• Propylene oxide
• Zinc oxide
• Cetylpyridinium chloride monohydrate
• 2-(Hydroxymethyl)pyridine
• 2,3,4-Trihydroxybenzoic acid