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PINOSYLVIN

Basic information Safety Supplier Related

PINOSYLVIN Basic information

Product Name:
PINOSYLVIN
Synonyms:
  • (e)-5-stilbenediol
  • 5-(2-phenylethenyl)-3-benzenedio(e)-
  • pinosylvine
  • AKOS 211-07
  • 3,5-DIHYDROXY-STILBENE
  • 3,5-TRANS-DIHYDROXYSTILBENE
  • 5-(2-Phenylethenyl)benzene-1,3-diol
  • 5-[(E)-2-Phenylethenyl]-1,3-benzenediol
CAS:
22139-77-1
MF:
C14H12O2
MW:
212.24
EINECS:
683-184-0
Product Categories:
  • Stilbenes (substituted)
Mol File:
22139-77-1.mol
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PINOSYLVIN Chemical Properties

Melting point:
153-157 °C
Boiling point:
312.08°C (rough estimate)
Density 
1.1035 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
2-8°C
solubility 
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:50): 0.01mg/mL; DMSO: 10mg/mL; Ethanol: 20mg/mL; Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL
form 
A solid
pka
9.34±0.10(Predicted)
BRN 
1870942
InChIKey
YCVPRTHEGLPYPB-VOTSOKGWSA-N
LogP
3.680 (est)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-36-51/53
Safety Statements 
26-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
WJ5580000
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PINOSYLVIN Usage And Synthesis

Chemical Properties

Off-white crystalline powder

Uses

Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.

Definition

ChEBI: Pinosylvin is a stilbenol.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Enzyme inhibitor

This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase.

PINOSYLVINSupplier

Chembest Research Laboratories Limited
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