DIETHYL ISOCYANOMETHYLPHOSPHONATE Chemical Properties

Boiling point:

84-87 °C0.1 mm Hg(lit.)

Density 

1.105 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.433(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

Liquid

color 

Clear colorless to yellow

BRN 

4674920

CAS DataBase Reference

41003-94-5

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36

WGK Germany 

3

F 

8-9

HS Code 

29319090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

DIETHYL ISOCYANOMETHYLPHOSPHONATE Usage And Synthesis

Chemical Properties

Clear colorless to yellow liquid

Uses

Reactant for:

• Copper-catalyzed cycloaddition reactions
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
• Synthesis of sterol analogs as antifungal agents against plant pathogens
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
• The Passerini reaction

DIETHYL ISOCYANOMETHYLPHOSPHONATE(41003-94-5)Related Product Information

• DIETHYL PHOSPHATE
• METHYL ISOCYANIDE
• DIETHYL ISOCYANOMETHYLPHOSPHONATE
• (Aminomethyl)phosphonic acid