TETRAMETHYL-1,3-CYCLOBUTANEDIONE Chemical Properties

Melting point:

114-116 °C(lit.)

Boiling point:

95-159 °C750 mm Hg(lit.)

Density 

1.0373 (rough estimate)

refractive index 

1.4580 (estimate)

Flash point:

120-122°C/150mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

It is soluble in chloroform.

form 

powder to crystal

color 

White to Almost white

InChIKey

RGCDVHNITQEYPO-UHFFFAOYSA-N

CAS DataBase Reference

933-52-8(CAS DataBase Reference)

EPA Substance Registry System

1,3-Cyclobutanedione, 2,2,4,4-tetramethyl- (933-52-8)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

GU1775000

TSCA 

Yes

HS Code 

2914290090

Hazardous Substances Data

933-52-8(Hazardous Substances Data)

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

TETRAMETHYL-1,3-CYCLOBUTANEDIONE Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

Tetramethyl-1,3-cyclobutanedione is used as a chemical for life science research. It is also used to make other chemical, as well as an chemical and organic intermediate.

Synthesis Reference(s)

Canadian Journal of Chemistry, 50, p. 3923, 1972 DOI: 10.1139/v72-619

Purification Methods

Crystallise the dione from *C6H6 and dry it in vacuo over P2O5 in an Abderhalden pistol. [Beilstein 7 III 3234, 7 IV 2004.]

TETRAMETHYL-1,3-CYCLOBUTANEDIONE(933-52-8)Related Product Information

• Tetramethylammonium nitrate
• (S,S)-(-)-2,3-DIHYDROXY-N,N,N',N'-TETRAMETHYLSUCCINAMIDE
• TETRAMETHYLSUCCINONITRILE
• 1,1,3,3-Tetramethyldisilazane
• 2,2,6,6-Tetramethyl-4-piperidinol
• TETRAMETHYLAMMONIUM HYDROGENSULFATE
• propanedial
• 2,2,4-TRIMETHYL-3-PENTANONE
• 2-methylpentane
• Pivaldehyde
• Cyclobutanone
• TETRAMETHYL-1,3-CYCLOBUTANEDIONE
• 2-METHYL-3-PENTANONE
• 2,2-Dimethylpentane
• 2,4-Dimethyl-3-pentanone
• CYCLOBUTANE
• Pinacolone
• Methyl valeraldehyde