PAROXETINE-D4 HCL Chemical Properties

Melting point:

121-131 C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent) and in methylene chloride.

form 

powder

color 

white

λmax

292nm(H2O)(lit.)

Merck 

14,7043

CAS DataBase Reference

110429-35-1

Safety Information

Hazard Codes 

F,C,Xn

Risk Statements 

11-34-36/37/38-22

Safety Statements 

16-26-36/37/39-45-36

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

TM4569320

HazardClass 

IRRITANT

HS Code 

29349990

PAROXETINE-D4 HCL Usage And Synthesis

Chemical Properties

White or almost white, crystalline powder.

Uses

Paroxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

Uses

Antidepressant;5-HT uptake inhibitor

Uses

Paroxetine hydrochloride hemihydrate has been used: as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro; as a CYP 2D6 inhibitor to study its effects on the in vitro?production by human recombinant CYP 2D6 of the phenolic metabolites; as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biochem/physiol Actions

Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant

PAROXETINE-D4 HCL(110429-35-1)Related Product Information

• trans N-Benzyl Paroxetine
• trans-(-)-3-[(1,3-Benzodioxol-5-yloxy)Methyl]-4-phenyl-1-(phenylMethyl)piperidine Hydrochloride
• rac-trans-4-Defluoro-4-ethoxy Paroxetine Hydrochloride
• trans 1-Benzyl-4-(4-fluorophenyl)-3-piperidinemethanol
• (3S,4R)-(-)-4-(4'-FLUOROPHENYL)3-HYDROXYMETHYL)-PIPERIDINE
• Dapoxetine hydrochloride
• Paroxetine
• Paroxetine hydrochloride
• 4-(4-FLUORO-PHENYL)-PIPERIDINE
• Piperidine hydrochloride
• PAROXETINE-D4 HCL