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2,5-DIDEOXY-2,5-IMINO-D-MANNITOL

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2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Basic information

Product Name:
2,5-DIDEOXY-2,5-IMINO-D-MANNITOL
Synonyms:
  • 2R,5R-BIS(HYDROXYMETHYL)-3R,4R-DIHYDROXYPYRROLIDINE
  • 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL
  • DMDP
  • 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine
  • (2R,5R)-bis(hydorxymethyl)-(3R,4R)-*dihydroxypyrr
  • (2R,5R)-BIS(HYDORXYMETHYL)-(3R,4R)-*DIHY DROXYPYRROL
  • 2,5-Pyrrolidinedimethanol, 3,4-dihydroxy-, (2R,3R,4R,5R)-
  • 2,5-Dideoxy-2,5-imino-L-mannitol
CAS:
59920-31-9
MF:
C6H13NO4
MW:
163.17
EINECS:
633-130-7
Product Categories:
  • Carbohydrates & Derivatives
  • All Inhibitors
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
  • Glycosidase Inhibitors
  • Inhibitors
Mol File:
59920-31-9.mol
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2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Chemical Properties

Melting point:
101-103°C
Boiling point:
395.9±37.0 °C(Predicted)
Density 
1.408±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
pka
13.67±0.70(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
CAS DataBase Reference
59920-31-9
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29400090

MSDS

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2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.

Uses

A glucosidase inhibitor.

Definition

ChEBI: 2,5-bis(hydroxymethyl)-3,4-dihydroxypyrrolidine is a dihydroxypyrrolidine.

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