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Ethyl 6-aminonicotinate

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Ethyl 6-aminonicotinate Basic information

Product Name:
Ethyl 6-aminonicotinate
Synonyms:
  • ETHYL 6-AMINOPYRIDINE-3-CARBOXYLATE
  • Ethyl 6-aminonicotinate 98%
  • 6-Amino-nicotinic acid ethyl esterr
  • Ethyl 6-aminonicotinate ,98%
  • 2-amino-5-(ethoxycarbonyl)pyridin-1-ium
  • 6-aminopyridine-3-carboxylate
  • 3-pyridinecarboxylic acid, 6-aMino-, ethyl ester
  • ETHYL 2-AMINOPYRIDINE-5-CARBOXYLATE
CAS:
39658-41-8
MF:
C8H10N2O2
MW:
166.18
Product Categories:
  • pharmacetical
  • Acids and Derivatives
  • Amines
  • blocks
  • Carboxes
  • Amines and Anilines
  • Pyridines
Mol File:
39658-41-8.mol
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Ethyl 6-aminonicotinate Chemical Properties

Melting point:
145-147
Boiling point:
314.7±22.0 °C(Predicted)
Density 
1.192±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
4.88±0.13(Predicted)
CAS DataBase Reference
39658-41-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
Hazard Note 
Irritant
HS Code 
2933399990
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Ethyl 6-aminonicotinate Usage And Synthesis

Synthesis

To a suspension of 1.3 g (9.4 mmol) 6-aminonicotinic acid in 100 mL of ethanol, was bubbled in dry hydrochloric acid at 0° C., then the solution was refluxed until all the solids dissolved. The solvents were removed under reduced pressure, the residue dissolved in ethyl acetate, washed with saturated sodium bicarbonate, brine, and concentrated to afford 1.37 g of a white solid Ethyl 6-Aminonicotinate.

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