4-Bromophenylacetonitrile Chemical Properties

Melting point:

47-49 °C (lit.)

Boiling point:

116-118°C 3mm

Density 

1.49

refractive index 

1.6550 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), Ethyl Acetate (Sparingly)

form 

Crystalline Mass

color 

Colorless to pale brown

Water Solubility 

slightly soluble

BRN 

1861069

Exposure limits

NIOSH: IDLH 25 mg/m3

InChIKey

MFHFWRBXPQDZSA-UHFFFAOYSA-N

CAS DataBase Reference

16532-79-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetonitrile, 4-bromo-(16532-79-9)

EPA Substance Registry System

4-Bromobenzyl cyanide (16532-79-9)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-20/21/22/36/37/39

Safety Statements 

26-36/37/39-38-26/36/37/39

RIDADR 

3276

WGK Germany 

3

RTECS 

AL8090000

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

MSDS

• Language:English Provider:4-Bromobenzyl cyanide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Bromophenylacetonitrile Usage And Synthesis

Chemical Properties

colorless to pale brown crystalline mass

Uses

4-Bromophenylacetonitrile has been used in the synthesis of :

• new fluorene-based alternating polymers
• light-emitting copolymer, poly(N ⁴,N ⁴-bis-(4-phenyl)-N ⁴,N ^4′-bis-[4-(2-ethylhexyloxy)phenyl]-biphenyl-4,4′-diamine-co-1,2-bis(4′-phenyl)-1-(9′′,9′′-dihexyl-3-fluorenyl)ethane) using a Yamamoto coupling reaction
• N-methyl-3,4-bis(4-(N-(1-naphthyl)phenylamino)phenyl)maleimide, a novel non-doped red organic light-emitting diode (OLED) material

Uses

4-Bromophenylacetonitrile is a chemical model used for the study and analysis of human buccal absorption of pharmaceuticals.

General Description

4-Bromophenylacetonitrile undergoes reduction using 1,1,3,3-tetramethyldisiloxane activated by a non-toxic titanium(IV) isopropoxide to yield 4-bromophenylethylamine.

Safety Profile

Poison by intravenous route. See also BROMIDES and NITRILES. When heated to decomposition it emits very toxic fumes of Br-, NOx, and CN-.

4-Bromophenylacetonitrile(16532-79-9)Related Product Information

• 4'-Bromoacetophenone
• 4-Methoxybenzyl cyanide
• Methyl 4-cyanobenzoate
• 4-Bromoaniline
• Cyanoacetic acid
• Methylene dithiocyanate
• Diphenylacetonitrile
• Benzyl bromide
• 2-Methylbenzyl cyanide
• Ethyl cyanoformate
• Benzyl 2-bromoacetate
• 4-Bromobiphenyl
• 2-(Chloromethyl)benzonitrile
• 4-Cyanophenol
• 4-Bromomethylbenzoic acid
• 4-Bromotoluene
• Copper(I) Cyanide
• ETHYL 2-CYANOACRYLATE