CYCLO (ARG-GLY-ASP-D-PHE-LYS)
CYCLO (ARG-GLY-ASP-D-PHE-LYS) Basic information
- Product Name:
- CYCLO (ARG-GLY-ASP-D-PHE-LYS)
- Synonyms:
-
- CYCLO(-RGDFK)
- CYCLO (ARG-GLY-ASP-D-PHE-LYS)
- cyclo (Arg-Gly-Asp-Phe-Lys)
- Cyclic RGDFK peptide
- Cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl)
- Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate salt
- c(RGDfK)
- Cyclo (-RGDfK) TFA
- CAS:
- 161552-03-0
- MF:
- C27H41N9O7
- MW:
- 603.67
- Product Categories:
-
- peptide
- RGD
- Mol File:
- Mol File
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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Chemical Properties
- Melting point:
- 191℃ (decomposition)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥30.19 mg/mL in DMSO; insoluble in EtOH; ≥59.2 mg/mL in H2O
- form
- Powder
- pka
- 4.01±0.10(Predicted)
- color
- White to off-white
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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Usage And Synthesis
Uses
Cyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.
Biological Activity
in one study where this peptide was labeled with 125i, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. the integrin alpha(iib)beta(3)-specific cyclic hexapeptide contains an arg-gly-asp (rgd) sequence.
target
Integrin
CYCLO (ARG-GLY-ASP-D-PHE-LYS)Supplier
Nanjing Peptide Biotech Ltd. Gold
- Tel
- 025-025-58361106-805-805 13082558573
- liugang@njpeptide.com
Nanjing TGpeptide Biotechnology Co.,Ltd. Gold
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- 18115476705
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Nanjing Yuanpeptide Biotech Co.，Ltd. Gold
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- 18168071971
- support@yuan-peptide.com
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd Gold
- Tel
- 13770887460
- wenxi@jszkhy.com
Nanchang Tianzhen Biotechnology Co., Ltd Gold
- Tel
- 13173652190
- pomy@tanzhenbio.com