Basic information Safety Supplier Related

(R)-2-amino-2-(4-hydroxyphenyl)acetamide

Basic information Safety Supplier Related

(R)-2-amino-2-(4-hydroxyphenyl)acetamide Basic information

Product Name:
(R)-2-amino-2-(4-hydroxyphenyl)acetamide
Synonyms:
  • (R)-2-amino-2-(4-hydroxyphenyl)acetamide
  • (2R)-2-Amino-2-(4-hydroxyphenyl)ace
  • (2R)-Amino-2-(4-hydroxyphenyl)acetamide
  • Benzeneacetamide, α-amino-4-hydroxy-, (αR)-
  • Amoxicillin Acetamide Impurity
CAS:
54397-23-8
MF:
C8H10N2O2
MW:
166.18
Mol File:
54397-23-8.mol
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(R)-2-amino-2-(4-hydroxyphenyl)acetamide Chemical Properties

solubility 
Aqueous Acid (Slightly), DMSO (Heated)
form 
Solid
color 
White to Pale Red
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(R)-2-amino-2-(4-hydroxyphenyl)acetamide Usage And Synthesis

Uses

D-p-Hydroxyphenylglycinamide is an activated side chain precursor and is an intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260), which is a potential impuritiy of the penicillins, ampicillin and amoxicillin, which have not been reported previously. 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone impurity may be formed during the semi-synthetic preparation of these antibiotics or upon their degradation.

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