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POLY(N-ISOPROPYL ACRYLAMIDE)

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POLY(N-ISOPROPYL ACRYLAMIDE) Basic information

Product Name:
POLY(N-ISOPROPYL ACRYLAMIDE)
Synonyms:
  • n-(1-methylethyl)-2-propenamidhomopolymer
  • poly(n-iso-propylacrylamide)(mw20000-25000)
  • Poly(N-isopropylacrylaMide) Mw 20,000-40,000
  • Poly(N-isopropylacrylaMide), carboxylic acid terMinated average Mn 10,000
  • nipam polymer
  • 2-Propenamid, N-(1-methylethyl)-, Homopolymer
  • 2-Propenamide, N-(1-methylethyl)-, homopolymer n-(1-methylethyl)-2-propenamid homopolymer
  • N-(1-Methylethyl)-2-propenamide homopolymer
CAS:
25189-55-3
MF:
C6H11NO
MW:
113.15764
Product Categories:
  • Acrylamides
  • Acrylics
  • Biomaterials
  • Hydrogels and Crosslinked Polymers
  • Hydrophilic Polymers
  • Materials Science
  • Polymer Science
  • Polymers
Mol File:
25189-55-3.mol
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POLY(N-ISOPROPYL ACRYLAMIDE) Chemical Properties

Melting point:
96 °C(lit.)
Density 
1.386 g/cm3
Tg
130
storage temp. 
-20°C
form 
powder
color 
white to off-white
EPA Substance Registry System
2-Propenamide, N-(1-methylethyl)-, homopolymer (25189-55-3)
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Safety Information

WGK Germany 
1

MSDS

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POLY(N-ISOPROPYL ACRYLAMIDE) Usage And Synthesis

Chemical Properties

mp 96°C phase transitions at 32°C to insoluble phase

Uses

PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Uses

Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Definition

ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide.

General Description

Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications.

Solubility in organics

Acetone, THF, water (cold)

POLY(N-ISOPROPYL ACRYLAMIDE)Supplier

Shenzhen Regent Biochemical Technology Co., Ltd. Gold
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0755-0755-85201366 18938635012
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sales@regentsciences.com
Shenzhen Polymeri Biochemical Technology Co., Ltd. Gold
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+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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market03@meryer.com
Bide Pharmatech Ltd.
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400-164-7117 13681763483
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product02@bidepharm.com
Finetech Industry Limited
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027-87465837 19945049750
Email
sales@finetechnology-ind.com