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2-Chloropyridine-5-boronic acid

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2-Chloropyridine-5-boronic acid Basic information

Product Name:
2-Chloropyridine-5-boronic acid
Synonyms:
  • 2-CHLORO-5-PYRIDYL BORONIC ACID
  • 2-Chloropyridine-5-boronic Acid (contains varying amounts of Anhydride)
  • 2-Chloropyridine-5-b
  • 2-choropyridine-5-boronic acid
  • 6-Chloropyridine-3-boronic acid (contains varying aMounts of Anhydride)
  • B-(6-Chloro-pyridin-3-yl)boronic acid
  • 2-chloro-5-pyridine acid
  • 6-Chloro-3-pyridylboronic
CAS:
444120-91-6
MF:
C5H5BClNO2
MW:
157.36
EINECS:
628-524-0
Product Categories:
  • pyridine series
  • Boronate Ester
  • Boronic acid
  • Organoborons
  • Boronic Acids & Esters
  • Potassium Trifluoroborate
  • BORONICACID
  • blocks
  • Boronic Acids & Esters
  • Boronic acids
  • B (Classes of Boron Compounds)
  • Chloropyridines
  • Halopyridines
  • Boric acid series
  • BoronicAcids
  • Pyridines
  • Pyridine
Mol File:
444120-91-6.mol
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2-Chloropyridine-5-boronic acid Chemical Properties

Melting point:
165 °C(lit.)
Boiling point:
336.9±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
6.70±0.10(Predicted)
color 
White to Light yellow
BRN 
9119810
InChIKey
WPAPNCXMYWRTTL-UHFFFAOYSA-N
CAS DataBase Reference
444120-91-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990

MSDS

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2-Chloropyridine-5-boronic acid Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

6-Chloro-3-pyridinylboronic acid can be used:

  • To prepare biologically significant 3-arylcoumarins by reacting with 3-chlorocoumarin through Suzuki reaction.
  • As a substrate in the synthesis of 11-(pyridinylphenyl)steroid with progesterone agonist/antagonist profile.
  • As a substrate in the preparation of α- secondary and tertiary pyridines by the reaction of pyridotriazoles with boronic acids.
  • As a substrate in the palladium-catalyzed α-arylation of saturated cyclic amines and N-methyl amines.

2-Chloropyridine-5-boronic acid Preparation Products And Raw materials

Raw materials

2-Chloropyridine-5-boronic acidSupplier

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