Cibenzoline Chemical Properties

Melting point:

103-104°

Boiling point:

449.2±45.0 °C(Predicted)

Density 

1.17±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

10.82±0.40(Predicted)

color 

White to Pale Yellow

CAS DataBase Reference

53267-01-9

Safety Information

Toxicity

LD100 in rats (mg/kg): 64 i.v. (Cognaco)

Cibenzoline Usage And Synthesis

Description

Cibenzoline is a structurally novel, class I (quinidine-like) antiarrhythmic agent. It has additional properties of class III and class IV compounds, delaying repolarization and antagonizing the positive inotropic effects of calcium.

Chemical Properties

Crystallized from petroleum ether, melting point 103~104°C. Acute toxicity LD50 (mg/kg): 64 IV. Cibenzoline Suecinate: C18H18N2?C4H6O4.[10067-32-8]. Crystallized from ethanol-ether, melting point 165°C

Originator

Hexachemie (France)

Uses

Cibenzoline acts as a highly active class I antiarrhythmic agent.

Uses

Cardiac depressant.

Definition

ChEBI: Cibenzoline is a diarylmethane.

brand name

CIPRALAN

Cibenzoline(53267-01-9)Related Product Information

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