4-Methoxybenzyl cyanide Chemical Properties

Melting point:

8 °C

Boiling point:

286-287 °C (lit.)

Density 

1.085 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.531(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

0.01g/l

form 

Liquid

Specific Gravity

1.085

color 

Clear colorless to slightly yellow

PH

4.5 (100g/l, H2O, 20℃)suspension

explosive limit

1.2-9.4%(V)

BRN 

509162

Exposure limits

NIOSH: IDLH 25 mg/m3

InChIKey

PACGLQCRGWFBJH-UHFFFAOYSA-N

CAS DataBase Reference

104-47-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetonitrile, 4-methoxy-(104-47-2)

EPA Substance Registry System

Benzeneacetonitrile, 4-methoxy- (104-47-2)

Safety Information

Hazard Codes 

Xn,T,Xi

Risk Statements 

20/21/22-36/37/38-52/53-25

Safety Statements 

26-37/39-36/37-61-45-36

RIDADR 

UN 3276 6.1/PG 3

WGK Germany 

3

RTECS 

AM0810000

F 

8

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269095

MSDS

• Language:English Provider:4-Methoxybenzyl cyanide
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4-Methoxybenzyl cyanide Usage And Synthesis

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

4-Methoxyphenylacetonitrile was used as starting reagent in the synthesis of :

• 2-(1-cyano-1-(2-methoxy)phenyl)methylidene-3-phenylthiazolidine-4,5-dione
• 2-(1-cyano-1-(4-methoxy)-phenyl)methylidene-3-phenylthiazolidine-4,5-dione
• α-cyanostilbenes

Uses

4-Methoxybenzyl cyanide is used in the biosynthesis of p-methoxyphenylacetic acid by immobilized Bacillus subtilis ZJB-063.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 15, p. 214, 1972 DOI: 10.1021/jm00272a029
Synthesis, p. 40, 1987 DOI: 10.1055/s-1987-27834

General Description

4-Methoxyphenylacetonitrile has been isolated from the sponge Psammaplysilla purpurea.

4-Methoxybenzyl cyanide(104-47-2)Related Product Information

• 4-Methoxyphenylacetic acid
• (3,4-Dimethoxyphenyl)acetonitrile
• 4'-Methoxyacetophenone
• 4-Methylbenzyl cyanide
• p-Anisaldehyde
• 4-Methoxybenzoic acid
• p-Anisidine
• Copper(I) Cyanide
• Benzeneacetonitrile
• Diphenylacetonitrile
• 2-Methylbenzyl cyanide
• 4-Methoxyphenethylamine
• 4-(Trifluoromethoxy)aniline
• 4-Methoxyphenylacetone
• 4-Formylbenzoic acid
• Methoxypropiophenone
• 4-Methoxyphenylboronic acid
• 4-Methoxybenzenesulfonyl chloride