7-Methylquinoline Chemical Properties

Melting point:

35-37 °C(lit.)

Boiling point:

258 °C(lit.)

Density 

1.061

refractive index 

1.6070 to 1.6210

Flash point:

>230 °F

storage temp. 

Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

5.44±0.14(Predicted)

form 

Viscous Liquid

color 

Off-White to Pale Beige Low-Melting

Water Solubility 

<0.1 g/100 mL at 20 ºC

BRN 

110317

Stability:

Stable. Incompatible with strong oxidizing agents, strong acids. May be light sensitive.

InChIKey

KDYVCOSVYOSHOL-UHFFFAOYSA-N

CAS DataBase Reference

612-60-2(CAS DataBase Reference)

NIST Chemistry Reference

Quinoline, 7-methyl-(612-60-2)

EPA Substance Registry System

7-Methylquinoline (612-60-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

37/38-41

Safety Statements 

26-39

WGK Germany 

3

RTECS 

VC0560000

TSCA 

Yes

HS Code 

29334900

MSDS

• Language:English Provider:7-Methylquinoline
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7-Methylquinoline Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

7-methylquinoline has been bioassayed as tumor initiator on the skin of Sencar mice.

General Description

7-Methylquinoline is a reagent used in the preparation of diarylmethylpiperazines as potent opioid receptor agonists with improved side effects. Also used in the preparation of novel pyrazine compounds derived from 2-phenylquinolin-7-yl which act as potent insulin-like growth factor-I receptor inhibitors.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

7-Methylquinoline may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

7-Methylquinoline is combustible.

Purification Methods

Purify it via its dichromate complex (m 149o, after five recrystallisations from water). [Cumper et al. J Chem Soc 1176 1962, Beilstein 20 III/IV 3497, 20/7 V 402.]

7-Methylquinoline(612-60-2)Related Product Information

• 6-Hydroxy-2(1H)-3,4-dihydroquinolinone
• Quinhydrone
• Isoquinoline
• Ethoxyquin
• quinolinium hydrogen sulphate
• 8-Hydroxyquinoline
• 8-Methylquinoline
• Quinclorac
• 4-METHYLQUINOLINE
• 4-Chloro-7-(trifluoromethyl)quinoline
• 7-(TRIFLUOROMETHYL)-4-QUINOLINOL
• 7-METHYL-8-NITROQUINOLINE
• 2,7-DIMETHYLQUINOLINE
• 7-Quinolinecarboxylic acid
• 7-TRIFLUOROMETHYL-4-QUINOLINETHIOL
• 4-CHLORO-2-METHYL-8-(TRIFLUOROMETHYL)QUINOLINE
• 4-HYDROXY-6-METHOXY-2-METHYLQUINOLINE
• 4-CHLORO-8-FLUORO-2-METHYLQUINOLINE