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DIGOXIGENIN

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DIGOXIGENIN Basic information

Product Name:
DIGOXIGENIN
Synonyms:
  • Digoxigenin Lanadigigenin
  • (3beta,5beta,12beta)-3,12,14-trihydroxycard-20(22)-enolide
  • 3β,12β,14-Trihydroxy-5β,20(22)-cardenolide, 5β,20(22)-Cardenolide-3β,12β,14-triol, Lanadigigenin, 3β,12β,14β,21-Tetrahydroxy-20(22)-norcholenic acid lactone
  • 3β,12β,14-Trihydroxy-5β,14β-card-20(22)-enolide
  • 3β,12β,14β-Trihydroxy-5β-carda-20(22)-enolide
  • δ20:22-3β,12β,14,21-tetrahydroxynorcholenic acid lactone
  • 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
  • 4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one
CAS:
1672-46-4
MF:
C23H34O5
MW:
390.51
EINECS:
216-806-2
Mol File:
1672-46-4.mol
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DIGOXIGENIN Chemical Properties

Melting point:
222 °C(lit.)
Boiling point:
435.71°C (rough estimate)
Density 
1.0639 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
room temp
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
14.44±0.70(Predicted)
color 
White to off-white
Merck 
13,3188
BRN 
96479
CAS DataBase Reference
1672-46-4(CAS DataBase Reference)
EPA Substance Registry System
Card-20(22)-enolide, 3,12,14-trihydroxy-, (3.beta.,5.beta,12.beta.)- (1672-46-4)
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Safety Information

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
36/37/39-45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
FH5390000
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
1672-46-4(Hazardous Substances Data)

MSDS

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DIGOXIGENIN Usage And Synthesis

Chemical Properties

Off-White to Pale Yellow Solid

Uses

cardiotonic, positive inotropic activity

Uses

DIGOXIGENIN is a steroid used as a probe in the detection of different viruses,it is also used as a non-isotopic label for DNA.

Uses

'Diagnosis;Mainly used as a non-isotopic label for DNA

Definition

ChEBI: Digoxigenin is a hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis. It has a role as a hapten and a plant metabolite. It is a 3beta-sterol, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It is a conjugate acid of a digoxigenin(1-). It derives from a hydride of a 5beta-cardanolide.

General Description

Digoxigenin is a therapeutic drug belonging to the group of cardiac glycosides, widely used in the management of congestive heart failure and other cardiac diseases.

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