Basic information High purity Guanidine carbonate synthesis method Reference quality standards Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Guanidine salt >  Guanidine carbonate

Guanidine carbonate

Basic information High purity Guanidine carbonate synthesis method Reference quality standards Safety Supplier Related

Guanidine carbonate Basic information

Product Name:
Guanidine carbonate
Synonyms:
  • Carbonic acid, compound with guanidine (1:2)
  • Guanidine·carbonic acid
  • Guanidne carbonate
  • Guanidinium carbonate, synthesis grade
  • Carbonicacid,compd.withguanidine(1:1)
  • Carbonicacid,compd.withguanidine(1:2)
  • Guanidonium-carbonat
  • Iminoureacarbonate
CAS:
593-85-1
MF:
C2H7N3O3
MW:
121.1
EINECS:
209-813-7
Product Categories:
  • Building Blocks
  • Chemical Synthesis
  • Guanidines
  • Nitrogen Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Organic Building Blocks
  • 593-85-1
Mol File:
593-85-1.mol
More
Less

Guanidine carbonate Chemical Properties

Melting point:
>300 °C(lit.)
Density 
1.25
vapor pressure 
0Pa at 25℃
storage temp. 
Store below +30°C.
solubility 
450g/l
form 
Crystalline Powder
pka
12.5[at 20 ℃]
color 
White to almost white
PH
11.7 (110g/l, H2O, 20℃)
Water Solubility 
450 g/L (20 ºC)
BRN 
3628359
InChIKey
KMSRVXJGTIRNNK-UHFFFAOYSA-N
LogP
-1.63 at 20℃
CAS DataBase Reference
593-85-1(CAS DataBase Reference)
NIST Chemistry Reference
Guanidine carbonate(593-85-1)
EPA Substance Registry System
Guanidine carbonate (2:1) (593-85-1)
More
Less

Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36-22
WGK Germany 
3
RTECS 
FG1750000
Autoignition Temperature
530 °C
TSCA 
Yes
HS Code 
29252000
Toxicity
LD50 orally in Rabbit: 1045 mg/kg

MSDS

More
Less

Guanidine carbonate Usage And Synthesis

High purity Guanidine carbonate synthesis method

Guanidine carbonate is an extremely versatile organic chemical products, it is mainly used in flame retardants, flocculants, foaming agents, synthetic sulfa drugs, etc. Guanidine carbonate is also used as synthetic detergent builders, high-quality cosmetics raw materials.Synthesis of guanidine carbonate is reported by many literatures [1-3] .The main domestic guanidine carbonate production is that molt dicyandiamide and ammonium chloride to generate guanidine hydrochloride, generate free guanidine under the action of the alkali, and then by the reaction of free guanidine and carbon dioxide to produce guanidine carbonate. this route is easy to generate melamine and its dimers, trimers and other impurities because of the high-temperature melting , and the presence of Cl-, Na + in the system is difficult to completely removed , even if the purity is> 99% of guanidine carbonate, its ash content is still up 0.2%, it is difficult to obtain high purity guanidine carbonate. in this paper, cyanamide as raw materials, reacts with carbon dioxide and ammonia in one step synthesis of guanidine carbonate, also known as ash-free guanidine carbonate, and then purify , to obtain a high purity guanidine carbonate, the reaction equation is as follows: 2NH2CN + CO2 + 2NH3 + H20 → [NH2C (: NH) NH2] 2H2CO3
Author: Zhouzhao Liang Xie Jianwei Zhou Xiaohong Jiang Yongqing
Author: Zhouzhao Liang, Xie Jianwei (Research Institute of Zhejiang University of West Branch Quzhou 324006)
Zhou Xiaohong, Jiang Yongqing (Institute of Fine Chemicals Group Technology Center Juhua Quzhou 324004)

Reference quality standards

[Industry Grade ] Name of Item Technical index
Premium grade B product
Appearance white crystalline white powder
Content of ≥ 99% 98%
Ammonium ≤ 0.45% 1.0%
Water insoluble matter ≤ 0.2% 0.2%
Moisture ≤ 0.2% 0.2%
Ash ≤ 0.15% 0.2%
Water-soluble test Qualified Qualified
PH value (4% 25 ℃) 11.4 11.4
[Pharmaceutical Grade ]
Name of Item Technical index
Premium grade
Appearance white crystals
Content ≥ 99%
Ammonium salt (with NH4Cl meter) ≤ 0.45%
Water insoluble matter ≤ 0.2%
Moisture ≤ 0.2%
Ash ≤ 0.1%
Water-soluble test Qualified
PH value (4% 25 ℃) 11.4
Heavy Metal ppm ≤10
Arsenic ppm ≤3
The above information is edited by the Chemicalbook of Tian Ye.

Chemical Properties

white to almost white crystalline powder. Soluble in water, slightly soluble in methanol, almost insoluble in acetone, benzene and ether.

Uses

Guanidine Carbonate is a strong organic alkali. It is used to adjust the pH of a formulation, organic intermediate, soap and cosmetic products.

Uses

Guanidine Carbonate is used in the cytidine triphosphate injection stabilization. It also acts as a powerful and versatile protein denaturants.
As a strong chemical base, guanidine carbonate is used as an intermediary in a variety of applications:
Organic synthesis materials and analytical reagents.
pH adjusting agents for amino resins, antioxidants, resin stabilizer and guanidine soap, also a grout agent, cement additives, surfactants.
In terms of synthetic detergent,it is used as a moisture agent and a synergist.
For Zinc, cadmium, manganese weight measurement, it is used as a precipitating agent, it is also used in the separation of alkali metal magnesium.

Application

Guanidine carbonate salt can be used as a reactant for the synthesis of:
An oxidizer, guanidinium dinitramide (GDN), by reacting with ammonium dinitramide.
Guanidinium cyclopropanecarboxylate by reacting with cyclopropanecarboxylic acid.

Preparation

Synthesis of guanidine carbonate: Melt double cyanide salts and ammonia to generate guanidine salts (guanidine hydrochloride, guanidine nitrate) at 170-230 ℃ . Then make guanidine salt into an alcohol solution, add soda to free guanidine, absorb carbon dioxide to obtain guanidine carbonate.

Hazard

Toxic by ingestion.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise it from MeOH. [Beilstein 3 H 86, 3 I 41, 3 II 72, 3 III 161, 3 IV 152.]

Guanidine carbonateSupplier

Guangdong wengjiang Chemical Reagent Co., Ltd. Gold
Tel
0751-2886750 13927877953
Email
3005811397@qq.com
Hubei Wande Chemical Co., Ltd Gold
Tel
027-59210159 15377098680
Email
1148280011@qq.com
Wuhan Rongcan Biotechnology Co., Ltd Gold
Tel
18327024450
Email
2130026275@qq.com
Suzhou yacoo science co.,Ltd Gold
Tel
0512-87182056 13451648594
Email
sales@yacoo.com.cn
XI'AN VEDA CHEMICAL CO.,LTD Gold
Tel
+86-29-88665278 13379235092
Email
sales@vedachem.com