Basic information Safety Supplier Related

UNCARINE D

Basic information Safety Supplier Related

UNCARINE D Basic information

Product Name:
UNCARINE D
Synonyms:
  • (3β,7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
  • Nsc113094
  • Speciophylline (Uncarine D)
  • Uncarin D
  • SPECIOPHYLLINE
  • UNCARINE D
  • Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aR,10'aS)-
CAS:
4697-68-1
MF:
C21H24N2O4
MW:
368.43
Mol File:
4697-68-1.mol
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UNCARINE D Chemical Properties

Melting point:
183~184℃
Boiling point:
555.2±50.0 °C(Predicted)
Density 
1.33
pka
13.56±0.60(Predicted)
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UNCARINE D Usage And Synthesis

Description

One of the alkaloids isolated from the leaves of Mitragyna speciosa, the structure of the base has been determined from the NMR spectrum which demonstrates that the alkaloid has a cis DIE ring junction and a conformation such that the oxindole ring deshields the ester methoxyl group.

Uses

Uncarine D is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.

Definition

ChEBI: Uncarine D is a member of indolizines.

References

Beckett et al., Sci. Pharm., Froc., 25th (1965)

UNCARINE DSupplier

Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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Biyu Biotechnology (Shanghai) Co., ltd
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021-26018599
EMMX Biotechnology LLC
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888-539-0666
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JinJin Le Chemical Co., Ltd
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10106090
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jjlchem2@163.com