1-cinnamoylpyrrolidine
1-cinnamoylpyrrolidine Basic information
- Product Name:
- 1-cinnamoylpyrrolidine
- Synonyms:
-
- 1-cinnamoylpyrrolidine
- 1-[(2E)-1-Oxo-3-phenyl-2-propenyl]pyrrolidine
- Cinnamopyrrolidide
- 2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)-
- 3-Phenyl-1-(pyrrolidin-1-yl)prop-2-en-1-one
- 1-Cinnamoylpyrrolidine, 10 mM in DMSO
- 3-PHENYL-1-PYRROLIDIN-1-YL-PROPENONE
- CAS:
- 52438-21-8
- MF:
- C13H15NO
- MW:
- 201.26
- Product Categories:
-
- Alkaloids
- Mol File:
- 52438-21-8.mol
1-cinnamoylpyrrolidine Chemical Properties
- Melting point:
- 123℃
- storage temp.
- Store at -20°C
- solubility
- Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
- form
- A solid
1-cinnamoylpyrrolidine Usage And Synthesis
Uses
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1]. 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].
Definition
ChEBI: 1-Cinnamoylpyrrolidine is an olefinic compound. It is functionally related to a cinnamic acid.
References
[1] Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. DOI:10.1016/j.bmc.2004.05.007
[2] Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24. DOI:10.1016/j.fitote.2007.04.009
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