5,6-DIHYDRO-2H-PYRAN-2-ONE Chemical Properties

Boiling point:

103 °C/10 mmHg (lit.)

Density 

1.139 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.483(lit.)

Flash point:

115 °F

storage temp. 

2-8°C

form 

clear liquid

color 

Colorless to Light orange to Yellow

Sensitive 

Moisture Sensitive

BRN 

1610

InChIKey

QBDAFARLDLCWAT-UHFFFAOYSA-N

CAS DataBase Reference

3393-45-1

Safety Information

Risk Statements 

10

Safety Statements 

23-24/25

RIDADR 

UN 1224 3/PG 3

WGK Germany 

3

F 

10-21

HazardClass 

3

PackingGroup 

III

HS Code 

2932209090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

5,6-DIHYDRO-2H-PYRAN-2-ONE Usage And Synthesis

Uses

5,6-Dihydro-2H-pyran-2-one has been used in the preparation of:

• (1aR,5aR,5bS,6S,7S)-6,7-di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran
• 4-(phenyl)tetrahydro-2H-pyran-2-one

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 1647, 1984 DOI: 10.1021/jo00183a030
Tetrahedron Letters, 25, p. 4783, 1984 DOI: 10.1016/S0040-4039(01)81518-5

General Description

Enantioselective conjugate addition of Grignard reagents to 5,6-dihydro-2H-pyran-2-one catalyzed by a chiral phosphine-copper iodide catalyst has been reported.

5,6-DIHYDRO-2H-PYRAN-2-ONE(3393-45-1)Related Product Information

• 5,6-DIHYDRO-2H-PYRAN-2-ONE
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