6-Chloropicolinic acid Chemical Properties

Melting point:

190-191°C

Boiling point:

241.15°C (rough estimate)

Density 

1.3768 (rough estimate)

refractive index 

1.5870 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol

pka

3.27±0.10(Predicted)

form 

Crystalline Powder

color 

White to cream to tan

Water Solubility 

3.40g/L(temperature not stated)

λmax

294nm(EtOH)(lit.)

BRN 

115849

InChIKey

ZLKMOIHCHCMSFW-UHFFFAOYSA-N

CAS DataBase Reference

4684-94-0(CAS DataBase Reference)

EPA Substance Registry System

6-Chloropicolinic acid (4684-94-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

2

RTECS 

TJ7535000

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

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6-Chloropicolinic acid Usage And Synthesis

Chemical Properties

Off-white Plates

Uses

6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.

6-Chloropicolinic acid(4684-94-0)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• 2-Chloro-5-chloromethylpyridine
• 2-Chloro-3-cyanopyridine
• Quinolinic acid
• 2,5-PYRIDINEDICARBOXYLIC ACID
• Clopidol
• 6-Chloroimidazo[2,1-f]pyridazine
• ETHYL 6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLATE
• 2-Amino-6-chloropyridine
• 2-Chloropyridine-5-sulfonyl chloride
• (6-Chloro-2-pyridinyl)methanol
• 5-CHLOROPICOLINIC ACID
• pyridinium Chlorochromate
• 2-Chloropyridine
• Picloram
• Clopyralid (2-hydroxyethyl)ammonium
• Tetrachloropyridine-2-carboxylic acid
• 6-CHLOROPYRIDINE-2,3-DICARBOXYLIC ACID DIMETHYL ESTER