Basic information Safety Supplier Related

6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER

Basic information Safety Supplier Related

6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Basic information

Product Name:
6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER
Synonyms:
  • 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER
  • Xanthylium, 9-2-carboxy-4-(2,5-dioxo-1-pyrrolidinyl)oxycarbonylphenyl-3,6-bis(dimethylamino)-, inner salt
  • 5-TAMRA, SE [5-Carboxytetramethylrhodamine, succinimidyl ester] *Single isomer*
  • 5-TAMRA,SE, >95%
  • 5-Carboxytetramethylrhodamine succinimidyl ester
  • 5-TAMRASE
  • "4-Carboxytetramethylrhodamine N-succinimidyl ester"
  • 5-TAMRA-SEor5-TAMRA-NHS
CAS:
150810-68-7
MF:
C29H25N3O7
MW:
527.53
Product Categories:
  • FLUOROPHORES
Mol File:
150810-68-7.mol
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6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Chemical Properties

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: soluble
form 
A solid
color 
Pale purple to purple
InChIKey
VWFRSNKRTNUMET-UHFFFAOYSA-N
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Safety Information

WGK Germany 
3
HS Code 
32049010
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6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Usage And Synthesis

Description

5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe. It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin , nucleotide diphosphate uridine-5’-diphosphate (UDP; ), and the progesterone receptor antagonist RU486 (mifepristone; ). 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.

Uses

Amine-reactive form of 5-carboxytetramethylrhodamine single isomer.

Uses

Amine-Reactive Fluorescent Probe for labeling of DNA and RNA

storage

Store at -20°C

6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTERSupplier

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