Cefaclor monohydrate
Cefaclor monohydrate Basic information
- Product Name:
- Cefaclor monohydrate
- Synonyms:
-
- (7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt
- Muco-panoral
- (6R,7R)-7-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3-chloro-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- (6R,7R)-7-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- Cefaclor (400 mg)
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-aMino-2-phenylacetyl]aMino]-3-chloro-8-oxo-, hydrate (1:1),(6R,7R)-
- CEFACLOR HYDRATE
- CAS:
- 70356-03-5
- MF:
- C15H16ClN3O5S
- MW:
- 385.82
- EINECS:
- 641-991-5
- Product Categories:
-
- Heterocycles
- Intermediates & Fine Chemicals
- Chiral Reagents
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Mol File:
- 70356-03-5.mol
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Cefaclor monohydrate Chemical Properties
- Melting point:
- >180°C (dec.)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Slightly soluble in water, practically insoluble in methanol and in methylene chloride.
- form
- Solid
- color
- White to Light Beige
- CAS DataBase Reference
- 70356-03-5(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xn,Xi
- Risk Statements
- 42/43-36
- Safety Statements
- 22-36/37-45
- WGK Germany
- 2
- RTECS
- XI0363000
- HS Code
- 2941906000
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Cefaclor monohydrate Usage And Synthesis
Description
Cefaclor was found by Eli Lilly & Co. in 1976 in the course of studies on the improvement of synthetic procedures for cephalexin. The intermediates with chlorine at the 3 position of the cephem nucleus have excellent antibacterial activity. Cefaclor was selected from among the various derivatives that differed at the 7 position because of its strong activity and high bioavailability following oral administration.
Chemical Properties
Crystalline Solid
Uses
Antibacterial;Bacterial transpeptidase inhibitor
Uses
Second-generation cephalosporin antibiotic. Antibacterial.
brand name
Ceclor (Lilly); Raniclor (Ranbaxy).
Contact allergens
Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions.
Cefaclor monohydrate Preparation Products And Raw materials
Raw materials
Cefaclor monohydrateSupplier
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Cefaclor monohydrate(70356-03-5)Related Product Information
- ALTRENOGEST
- Tetraacetylethylenediamine
- N-ACETYL-L-TYROSINE ETHYL ESTER
- 4,4'-Diacetylbiphenyl
- MELIBIOSE
- Cephalexin
- Cefaclor
- Glycine
- 3,4'-DIAMINODIPHENYLMETHANE
- Cefadroxil
- D(-)-Phenylglycinamide
- 7-Amino-3-chloro cephalosporanic acid
- 2-Chloroethyl ethyl sulfide
- CIS-3-CHLOROACRYLIC ACID
- 2-Acetamidoacrylic acid
- 2-CHLOROETHYL METHYL SULFIDE
- Cefalexin Extend-release Tablet
- Cefaclor Dispensible Tablet