Prednisolone succinate
Prednisolone succinate Basic information
- Product Name:
- Prednisolone succinate
- Synonyms:
-
- PREDNISOLONE 21-HEMISUCCINATE
- prednisolone 21-(hydrogen succinate)
- D1-Hydrocortisone 21-hemisuccinate
- Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-, 21-(hydrogen succinate) (6CI, 7CI, 8CI)
- Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)- (9CI)
- Δ1-Hydrocortisone 21-hemisuccinate, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate, 1,4-Pregnadiene-11β,17,21-triol-3,20-dione 21-hemisuccinate
- 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(4-oxo-4-hydroxybutyrate)
- 21-(3-Carboxy-1-oxopropoxy)-11β,17-dihydroxypregna-1,4-diene-3,20-dione
- CAS:
- 2920-86-7
- MF:
- C25H32O8
- MW:
- 460.52
- EINECS:
- 220-861-8
- Product Categories:
-
- RISPERDAL
- Mol File:
- 2920-86-7.mol
Prednisolone succinate Chemical Properties
- Melting point:
- 206°C
- Boiling point:
- 485.35°C (rough estimate)
- alpha
- [α]D20 +99～+104゜ (c=0.5, 1,4-dioxane)
- Density
- 1.1796 (rough estimate)
- refractive index
- 1.4480 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 4.29±0.17(Predicted)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 2920-86-7(CAS DataBase Reference)
Safety Information
- Risk Statements
- 61-40
- Safety Statements
- 53-22-36/37/39-45
- WGK Germany
- 3
- RTECS
- TU4153400
- HS Code
- 2937290000
Prednisolone succinate Usage And Synthesis
Uses
neuroleptic
Uses
Prednisolone hemisuccinate, is a metabolite of Prednisolone (P703740), which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. It is also the active metabolite of the drug prednisone.
Definition
ChEBI: Prednisolone succinate is a hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. It has a role as an anti-inflammatory drug. It is a hemisuccinate, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisolone and a succinic acid. It is a conjugate acid of a prednisolone succinate(1-).
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Prednisolone succinate(2920-86-7)Related Product Information
- Succinic acid
- Methylprednisolone
- Prednisolone
- Hydrogen
- Disodium succinate
- Methylprednisolone acetate
- Prednisolone-21-acetate
- D-α-Tocopherol succinate
- 6alpha-Methylprednisolone sodium succinate
- Meprednisone
- Hydrocortisone
- Prednisone
- Hydrocortisone 21-hemisuccinate
- HYDROGEN CYANIDE
- Prednisolone sodium succinate
- Hydrogen peroxide
- CI 46045
- Prednisolone succinate