(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Chemical Properties

Melting point:

>160°C (dec.)

Boiling point:

675.1±55.0 °C(Predicted)

Density 

1.437±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

pka

2.20±0.10(Predicted)

color 

Light Yellow

Water Solubility 

Soluble to 50 mM in water with gentle warming

(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID Usage And Synthesis

Uses

MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed.

Biological Activity

Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.

storage

-20°C (protect from light)

(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID(295325-62-1)Related Product Information

• (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
• 5-METHOXY-N-METHYL-2-NITROBENZENAMINE
• 7-NITRO-2,3-DIHYDRO-1H-INDOLE
• 2'-Methyl-3'-methoxyacetanilide
• 4-Methoxy-2,3-dihydro-1H-indole
• indoline-4-ol
• 1-ACETYL-7-AMINO-2,3-DIHYDRO-(1H)-INDOLE