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1,6,7-Trihydroxyxanthone

Basic information Safety Supplier Related

1,6,7-Trihydroxyxanthone Basic information

Product Name:
1,6,7-Trihydroxyxanthone
Synonyms:
  • 1,6,7-Trihydroxyxanthone
  • 1,6,7-Trihydroxy-9H-xanthen-9-one
  • 9H-Xanthen-9-one, 1,6,7-trihydroxy-
  • 7-Trihydroxyxanthone
  • 1,6,7-trihydroxyxanthen-9-one
CAS:
25577-04-2
MF:
C13H8O5
MW:
244.2
Mol File:
25577-04-2.mol
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1,6,7-Trihydroxyxanthone Chemical Properties

storage temp. 
2-8°C
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1,6,7-Trihydroxyxanthone Usage And Synthesis

Uses

1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1].

References

[1] Fu WM, et al. MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells. Apoptosis. 2015 Jan;20(1):75-82. DOI:10.1007/s10495-014-1047-3

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