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Di-tert-butyl N,N-diethylphosphoramidite

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Di-tert-butyl N,N-diethylphosphoramidite Basic information

Product Name:
Di-tert-butyl N,N-diethylphosphoramidite
Synonyms:
  • DI-T-BUTYL N,N-DIETHYLPHOSPHORAMIDITE
  • DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE
  • DI-TERT-BUTYL N,N-DIETHYLPHOSPHORAMIDITE
  • DI-TERT-BUTYL-N,N-DIETHYLPHOSPHOROAMIDITE
  • DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE, TE CH., 93%
  • Diethyl diethylphosphoramidite
  • N,N-Diethyl-phosphoraMidous Acid Bis(1,1-diMethylethyl) Ester
  • Phosphoramidous acid, diethyl-, bis(1,1-dimethylethyl) ester
CAS:
117924-33-1
MF:
C12H28NO2P
MW:
249.33
Product Categories:
  • Phospholipids - 13C & 2H
  • Regant series
  • Phosphorylating and Phosphitylating Agents
  • Organic Building Blocks
  • Phosphoramidites
  • Phosphorus Compounds
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Phosphorus Compounds
  • OLED materials,pharm chemical,electronic
Mol File:
117924-33-1.mol
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Di-tert-butyl N,N-diethylphosphoramidite Chemical Properties

Boiling point:
39-41 °C/0.3 mmHg (lit.)
Density 
0.896 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.434(lit.)
Flash point:
173 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
4.41±0.70(Predicted)
form 
Oil
color 
Clear Colourless
Water Solubility 
Hydrolyzes in water. Soluble in chloroform and methanol.
Sensitive 
Moisture Sensitive
BRN 
4175262
Stability:
Moisture Sensitive
CAS DataBase Reference
117924-33-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
4.4-10-21
HS Code 
29319090

MSDS

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Di-tert-butyl N,N-diethylphosphoramidite Usage And Synthesis

Chemical Properties

Clear Colourless Liquid

Uses

A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

Uses

Di-tert-butyl N,N-diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters.

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