DISUCCINIMIDYL SUBERATE Chemical Properties

Melting point:

169-170°C

Boiling point:

513.5±60.0 °C(Predicted)

Density 

1.295 g/cm3

storage temp. 

2-8°C

solubility 

chloroform: 50 mg/mL

form 

powder

color 

White to Almost white

Water Solubility 

Insoluble in water. Soluble in chloroform: 50 mg/mL.

InChIKey

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

CAS DataBase Reference

68528-80-3

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29171900

MSDS

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DISUCCINIMIDYL SUBERATE Usage And Synthesis

Description

DSS Crosslinker is a membrane permeable, noncleavable crosslinker. The NHS ester groups are reactive toward primary amines.

Uses

Suberic acid bis(N-hydroxysuccinimide ester) has been:

• supplemented in pierce lysis buffer used for immunoprecipitation
• used to conjugate the oligonucleotide standards to gelatin
• used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers

Uses

Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.

Uses

Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

General Description

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

DISUCCINIMIDYL SUBERATE(68528-80-3)Related Product Information

• BS3
• 1,2-DiMyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) SodiuM Salt
• Suberic acid
• Suberate Bis(sulfosuccinimidyl) Sodium Salt
• Disuccinimidyl glutarate
• EGS Crosslinker
• ETHYLENE GLYCOL DISUCCINATE BIS(SULFO-N-
• Glycolic acid
• Polysuccinimide
• Azelaic acid
• dihexyl octanedioate
• Trimethoxyoctylsilane
• 4-(MALEINIMIDO)PHENYL ISOCYANATE*
• 4-(N-Maleimido)benzophenone
• 2-Maleimido acetic acid
• DISUCCINIMIDYL SEBACATE
• 4-Maleimidobenzoic acid
• N-Succinimidyl maleimidoacetate