- Product Name:
- Glycine hydrochloride
- GLYCINE HYDROCHLORIDE SOLUTION
- Glycine hydrochloride, BR,99%
- Glycocol hydrochloride
- Glycine solution hydrochloride
- Glycine hydrochloride,99%
- Product Categories:
- food ingredients
- Amino Acids, Peptides and Proteins
- Amino AcidsAnalytical Standards
- Life Sciences Standards
- alpha-Amino Acids
- Amino Acids
- omega-Aminocarboxylic Acids
- omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
- Mol File:
Glycine hydrochloride Chemical Properties
- Melting point:
- 176-180 °C(lit.)
- 1.457[at 20℃]
- vapor pressure
- 0.003Pa at 20℃
- storage temp.
- Crystalline Powder
- White to almost white
- Water Solubility
- SLIGHTLY SOLUBLE
- -3.25 at 20℃
- CAS DataBase Reference
- 6000-43-7(CAS DataBase Reference)
- EPA Substance Registry System
- Glycine, hydrochloride (6000-43-7)
Glycine hydrochloride Usage And Synthesis
white crystals or crystalline powder
Glycine hydrochloride is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.Glycine Hydrochloride is commonly used in buffer solutions, in electrophoresis, and preparative chromatography.
Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues.
Glycine hydrochloride has been used:
in the preparation of glycine-HCl buffer
to elute serum immunoglobulins (IgGs) from the beads in order to check for the complete enrichment of core- and site-specific antibodies
to regenerate the sensor to elute the bound C-reactive protein (CRP)
Glycine hydrochloride is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Glycine hydrochloride can be prepared by the action of hydrochloric acid on hippuric acid,aminoacetonitrile,methyleneaminoacetonitrile, and on ethyl phthaliminoacetate. Aniline has been recommended for its conversion into free glycine. Glycine can also be prepared by the interaction of chloroacetic acid and ammonia; by the hydrolysis of methyleneaminoacetonitrile by successive treatments with barium hydroxide and sulfuric acid; and by the hydrolysis of aminoacetonitrile by means of barium hydroxide. A thorough study has been reported for its preparation in improved yields by the sulfuric acid hydrolysis of aminoacetonitrile, and in satisfactory yields from chloroacetic acid and ammonia. Other methods of preparation include the reduction of cyanoformic esters, a modified Curtius degradation of ethyl cyanoacetate, and the hydrolysis of the neck ligaments of cattle.
synthesis of Glycine hydrochloride
Flammability and Explosibility
Glycine acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.
Glycine comprises a single carbon molecule, that is attached to the amino and a carboxyl group. Glycine hydrochloride (Gly·HCl) is capable of liquifying native chitosan and also helps in the preparation of regenerated chitosan membrane. It can serve as an osmoprotectant. Glycine can act as a flexible link in proteins and can also allow the formation of helices. Free glycine may have a protecting role in tissues against ischemia, hypoxia and reperfusion.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Crystallise the salt from absolute EtOH or 80% EtOH. Monoglycine hydrochloride has m 176-177o, and diglycine monohydrochloride has m 187o. [Frost J Am Chem Soc 64 1286 1942, Beilstein 4 III 1111, 4 IV 2353.]
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- DL-4-CHLOROPHENYLALANINE ETHYL ESTER HYDROCHLORIDE
- Methyl L-leucinate hydrochloride
- Diethyl aminomalonate hydrochloride
- 1-Aminocyclopropane-1-carboxylic acid hydrochloride
- DL-4-Chlorophenylalanine methyl ester hydrochloride
- Betaine hydrochloride
- L-Valine methyl ester hydrochloride
- Ethyl L-methionate hydrochloride
- L-Methionine methyl ester hydrochloride
- Glycine hydrochloride
- Glycine methyl ester hydrochloride
- Topotecan hydrochloride
- Glycine ethyl ester hydrochloride
- 4-Aminophenylacetic acid