DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID Chemical Properties

Melting point:

227-229 °C(lit.)

storage temp. 

0-6°C

solubility 

Water (Slightly, Heated)

form 

solid

color 

Light Brown

CAS DataBase Reference

20263-06-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29310099

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID Usage And Synthesis

Chemical Properties

white to almost white powder

Uses

DL-2-Amino-3-phosphonopropionic acid (AP3) is an inhibitor of phosphoserine phosphatase and mGluR. Also known as the antagonist of a receptor that is coupled to phosphoinositide metabolism in brain slices. D,L-2-Amino-3-phosphonopropionic acid is also an inhibitor of metabotropic glutamate receptors in rat brain.

Definition

ChEBI: 2-amino-3-phosphonopropanoic acid is a non-proteinogenc alpha-amino acid that is alanine in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group. It has a role as a metabotropic glutamate receptor antagonist and a human metabolite. It is a non-proteinogenic alpha-amino acid, a member of phosphonic acids and an alanine derivative.

Biological Activity

Competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID(20263-06-3)Related Product Information

• sodium N-dodecyl-beta-alaninate
• D-Alanine
• Fluticasone propionate
• Clobetasol propionate
• 3-PHOSPHONOPROPIONIC ACID
• D-AP3
• AURORA KA-2968
• 2-(ethoxycarbonyl)-2-aminoethyl dihydrogen phosphate
• DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID
• L-AP3