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Isosparteine

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Isosparteine Basic information

Product Name:
Isosparteine
Synonyms:
  • (7S,7aβ,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
  • (7S,7aβ,14S,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
  • Isosparteine
  • β-Isosparteine
  • b-Isosparteine
  • 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine,dodecahydro-, (7S,7aS,14S,14aS)-
  • Isosparteine USP/EP/BP
  • β-Sparteine
CAS:
24915-04-6
MF:
C15H26N2
MW:
234.38
Mol File:
24915-04-6.mol
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Isosparteine Chemical Properties

alpha 
D32 -15.3° (c = 2.3 in abs alc)
Boiling point:
bp0.2 100-110°
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Isosparteine Usage And Synthesis

Uses

Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor)[1][2].

References

[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014
[2] Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57(4):1646-53. DOI:10.1021/jf803468q

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