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Isosparteine
Isosparteine Basic information
- Product Name:
- Isosparteine
- Synonyms:
-
- (7S,7aβ,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
- (7S,7aβ,14S,14aβ)-Dodecahydro-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
- Isosparteine
- β-Isosparteine
- b-Isosparteine
- 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine,dodecahydro-, (7S,7aS,14S,14aS)-
- Isosparteine USP/EP/BP
- β-Sparteine
- CAS:
- 24915-04-6
- MF:
- C15H26N2
- MW:
- 234.38
- Mol File:
- 24915-04-6.mol
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Isosparteine Chemical Properties
- alpha
- D32 -15.3° (c = 2.3 in abs alc)
- Boiling point:
- bp0.2 100-110°
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
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Isosparteine Usage And Synthesis
Uses
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor)[1][2].
References
[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014
[2] Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57(4):1646-53. DOI:10.1021/jf803468q
IsosparteineSupplier
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