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Hydrocortisone-17-butyrate

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Hydrocortisone-17-butyrate Basic information

Product Name:
Hydrocortisone-17-butyrate
Synonyms:
  • HYDROCORTISONE 17-BUTYRATE
  • HYDROCORTISONE BUTYRATE
  • CORTISOL 17-BUTYRATE
  • 11b,17,21-trihydroxypregn-4-ene-3,20-dione 17-butyrate
  • 11BETA,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE 17-BUTYRATE
  • 11-beta,17-alpha,21-trihydroxy-4-pregnene-3,20-dione17-alpha-butyrate
  • h.17b
  • hb(sub17)
CAS:
13609-67-1
MF:
C25H36O6
MW:
432.56
EINECS:
237-093-4
Product Categories:
  • NOVANTRONE
  • Steroid and Hormone
  • Steroids
Mol File:
13609-67-1.mol
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Hydrocortisone-17-butyrate Chemical Properties

Melting point:
210.0 to 214.0 °C
Boiling point:
466.2°C (rough estimate)
Density 
1.0914 (rough estimate)
refractive index 
1.4593 (estimate)
pka
12.98±0.10(Predicted)
form 
neat
Merck 
14,4787
CAS DataBase Reference
13609-67-1(CAS DataBase Reference)
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Safety Information

WGK Germany 
2
RTECS 
GM9002000
HS Code 
2937290000

MSDS

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Hydrocortisone-17-butyrate Usage And Synthesis

Uses

antineoplastic

Uses

Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent.

Uses

Hydrocortisone-17-butyrate is a topical corticosteroid with anti-inflammatory properties; marker for topical corticosteroid allergy.

Definition

ChEBI: Cortisol esterified with butyric acid at the 17-hydroxy group.

brand name

Locoid (Ferndale); Locoid (Yamanouchi).

Contact allergens

Hydrocortisone 17-butyrate is a C 17 ester of hydrocorti- sone. It represents the D2 group of corticosteroids, non C 16 methylated with a C 17 ester: hydrocortisone 17-butyrate, hydrocortisone 17-valerate, hydrocortisone aceponate (17-propionate and 21-acetate), methylpred- nisolone aceponate, and prednicarbate. It is sometimes hydrolyzed in vivo into hydrocortisone, giving allergic reactions to group-A-sensitized people.

Hydrocortisone-17-butyrateSupplier

Wellman Pharmaceutical Group Limited Gold
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027-83778875-
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15807197853@163.com
CHANGZHOU GARDE PHARMTECH CO.,LTD Gold
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gardepharm@163.com;gardepharm@163.com
Hubei Qibu New Material Technology Co., Ltd. Gold
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0715-8890696
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J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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jkinfo@jkchemical.com;market6@jkchemical.com
TCI (Shanghai) Development Co., Ltd.
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021-67121386 / 800-988-0390
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Sales-CN@TCIchemicals.com