Hydrocortisone-17-butyrate Chemical Properties

Melting point:

210.0 to 214.0 °C

Boiling point:

466.2°C (rough estimate)

Density 

1.0914 (rough estimate)

refractive index 

1.4593 (estimate)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

12.98±0.10(Predicted)

color 

White to Off-White

Merck 

14,4787

CAS DataBase Reference

13609-67-1(CAS DataBase Reference)

Safety Information

WGK Germany 

2

RTECS 

GM9002000

HS Code 

2937290000

MSDS

• Language:English Provider:SigmaAldrich

Hydrocortisone-17-butyrate Usage And Synthesis

Uses

antineoplastic

Uses

Hydrocortisone-17-butyrate is a topical corticosteroid with anti-inflammatory properties; marker for topical corticosteroid allergy.

Uses

Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent.

Definition

ChEBI: Cortisol esterified with butyric acid at the 17-hydroxy group.

brand name

Locoid (Ferndale); Locoid (Yamanouchi).

Contact allergens

Hydrocortisone 17-butyrate is a C 17 ester of hydrocorti- sone. It represents the D2 group of corticosteroids, non C 16 methylated with a C 17 ester: hydrocortisone 17-butyrate, hydrocortisone 17-valerate, hydrocortisone aceponate (17-propionate and 21-acetate), methylpred- nisolone aceponate, and prednicarbate. It is sometimes hydrolyzed in vivo into hydrocortisone, giving allergic reactions to group-A-sensitized people.

Biochem/physiol Actions

Hydrocortisone 17-butyrate is a corticosteroid that acts as a dermocorticoid due to its application in dermatological therapy. It exhibits therapeutic effects against vitiligo of the face and neck.

Hydrocortisone-17-butyrate(13609-67-1)Related Product Information

• Flumethasone
• Progesterone
• Hydrocortisone
• 3,20-Dioxopregn-4-en-17-beta-yl acetate
• Hydrocortisone-17-butyrate
• FEMA 3332
• CORTEXOLONE
• CORTICOSTERONE
• CORTISONE
• Butyric Acid
• 11BETA-HYDROXYPROGESTERONE
• Desoxycorticosterone
• Amebucort
• Hydrocortisone Butyrate Propionate
• CORTISOL 17-VALERATE
• 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
• 3-ACETOXY-3-METHYL-2-BUTANONE
• 17ALPHA-HYDROXYPROGESTERONE