Basic information Brand Name(s) in US Safety Supplier Related
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Piperacillin sodium salt

Basic information Brand Name(s) in US Safety Supplier Related

Piperacillin sodium salt Basic information

Product Name:
Piperacillin sodium salt
Synonyms:
  • PIPERACILLIN SODIUM
  • PIPERACILLIN NA
  • [2s-[2alpha,5alpha,6beta(s*)]]-6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
  • (2s-(2-alpha,5-alpha,6-beta(s*)))-msal
  • 3-dimethyl-7-oxo--piperazinyl)carbonyl)amino)phenylacetyl)amino)-monosodiu
  • 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(((((4-ethyl-2,3-dioxo-1
  • cl227193
  • pentcillin
CAS:
59703-84-3
MF:
C23H26N5NaO7S
MW:
539.54
EINECS:
261-868-6
Product Categories:
  • Interferes with Cell Wall SynthesisSpectrum of Activity
  • Antibacterial
  • Antibiotics
  • Antibiotics A to
  • Antibiotics N-SAntibiotics
  • Chemical Structure Class
  • Antibiotics for Research and Experimental Use
  • beta-Lactams (Antibiotics for Research and Experimental Use)
  • Biochemistry
  • Antibiotic Explorer
  • L - ZAntibiotics
  • Mechanism of Action
  • Penicillins and Cephalosporins (beta-Lactams)
  • PIPRACIL
  • 59703-84-3
Mol File:
59703-84-3.mol
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Piperacillin sodium salt Chemical Properties

Melting point:
183-185 C (dec.)
Boiling point:
793℃
refractive index 
180 ° (C=0.8, H2O)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: 50 mg/mL, clear, colorless to faintly yellow
form 
Solid
color 
White to Almost white
Water Solubility 
Soluble in ethanol, water and methanol.
Merck 
14,7463
BRN 
5373920
Stability:
Hygroscopic
InChIKey
WCMIIGXFCMNQDS-IDYPWDAWSA-M
CAS DataBase Reference
59703-84-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
42/43
Safety Statements 
22-36/37-45
WGK Germany 
2
RTECS 
XI0180000
HS Code 
29411099
Toxicity
LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai)
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Piperacillin sodium salt Usage And Synthesis

Brand Name(s) in US

Pipracil

Description

Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.

Chemical Properties

White to off-white crystalline powder

Uses

Penicillin antibacterial.

Uses

A broad spectrum antibiotic targeting a wide range of susceptible gram positive and gram negative bacteria. Piperacillin sodium salt is an antibiotic. It is used in pharmacokinetic studies to optimize antimicrobial therapy and in hypersensitivity reactions. It is involved in the study of multidrug-resistant organisms. It acts as an antibiotic related to penicillin.

Definition

ChEBI: Piperacillin sodium is an organic sodium salt. It contains a piperacillin(1-).

brand name

Pipracil (Wyeth).

Piperacillin sodium saltSupplier

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