4-β-D-Glucopyranosyloxybenzeneethanol
4-β-D-Glucopyranosyloxybenzeneethanol Basic information
- Product Name:
- 4-β-D-Glucopyranosyloxybenzeneethanol
- Synonyms:
-
- 4-β-D-Glucopyranosyloxybenzeneethanol
- Icariside D2
- β-D-Glucopyranoside, 4-(2-hydroxyethyl)phenyl
- CAS:
- 38954-02-8
- MF:
- C14H20O7
- MW:
- 300.3
- Mol File:
- 38954-02-8.mol
4-β-D-Glucopyranosyloxybenzeneethanol Chemical Properties
- form
- Solid
- color
- White to off-white
4-β-D-Glucopyranosyloxybenzeneethanol Usage And Synthesis
Uses
Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2].
Definition
ChEBI: Icariside D2 is a glycoside.
References
[1] Nguyen Thi Thu Hien, et al. Chemical Constituents of the Annona Glabra Fruit and Their Cytotoxic Activity. Pharm Biol. 2015;53(11):1602-7. DOI:10.3109/13880209.2014.993042
[2] Xue Liu, et al. Metabolic Engineering Escherichia coli for Efficient Production of Icariside D2. Biotechnol Biofuels. 2019 Nov 6;12:261. DOI:10.1186/s13068-019-1601-x
[3] Jin-YuLi, et al. Three new acylated prenylflavonol glycosides from Epimedium koreanum. Phytochemistry Letters Volume 17, September 2016, Pages 206-212.
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