Basic information Safety Supplier Related

4-β-D-Glucopyranosyloxybenzeneethanol

Basic information Safety Supplier Related

4-β-D-Glucopyranosyloxybenzeneethanol Basic information

Product Name:
4-β-D-Glucopyranosyloxybenzeneethanol
Synonyms:
  • 4-β-D-Glucopyranosyloxybenzeneethanol
  • Icariside D2
  • β-D-Glucopyranoside, 4-(2-hydroxyethyl)phenyl
CAS:
38954-02-8
MF:
C14H20O7
MW:
300.3
Mol File:
38954-02-8.mol
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4-β-D-Glucopyranosyloxybenzeneethanol Chemical Properties

form 
Solid
color 
White to off-white
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4-β-D-Glucopyranosyloxybenzeneethanol Usage And Synthesis

Uses

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2].

Definition

ChEBI: Icariside D2 is a glycoside.

References

[1] Nguyen Thi Thu Hien, et al. Chemical Constituents of the Annona Glabra Fruit and Their Cytotoxic Activity. Pharm Biol. 2015;53(11):1602-7. DOI:10.3109/13880209.2014.993042
[2] Xue Liu, et al. Metabolic Engineering Escherichia coli for Efficient Production of Icariside D2. Biotechnol Biofuels. 2019 Nov 6;12:261. DOI:10.1186/s13068-019-1601-x
[3] Jin-YuLi, et al. Three new acylated prenylflavonol glycosides from Epimedium koreanum. Phytochemistry Letters Volume 17, September 2016, Pages 206-212.

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