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BUPROPION MORPHOLINOL

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BUPROPION MORPHOLINOL Basic information

Product Name:
BUPROPION MORPHOLINOL
Synonyms:
  • BUPROPION MORPHOLINOL
  • (2R,3R)-2-(-3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol
  • 2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol
  • Bupropion Morpholinol (Mixture of stereoisoMers)
  • 2-(3-Chlorophenyl)-3,5,5-triMethyl-
  • Bupropion Impurity 12
  • Bupropion Hydroxy Cyclic Impurity
  • Bupropion Morpholinol (Hydroxy Bupropion)
CAS:
357399-43-0
MF:
C13H18ClNO2
MW:
255.74
Product Categories:
  • Metabolite
  • Isotope
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
357399-43-0.mol
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BUPROPION MORPHOLINOL Chemical Properties

Melting point:
121-123°C
Boiling point:
386.6±42.0 °C(Predicted)
Density 
1.144±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml
form 
A crystalline solid
pka
11.90±0.60(Predicted)
color 
White to off-white
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BUPROPION MORPHOLINOL Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3’-chlorophenyl)-355-trimethylmorpholine). See US Pat. # 634.2496

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