PGD-M Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

PGD-M Usage And Synthesis

Description

Prostaglandin D₂ (PGD₂) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD₂ with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD₂.

Uses

Labelled PGD-M

Uses

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.

Uses

PGD-M is the major urinary metabolite of PGD2 in humans.

References

[1] H. GILES  P. L. The biology and pharmacology of PGD2[J]. Prostaglandins, 1988, 35 2: Pages 277-300. DOI: 10.1016/0090-6980(88)90093-7
[2] JASON D. MORROW. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay[J]. Analytical biochemistry, 1991, 193 1: Pages 142-148. DOI: 10.1016/0003-2697(91)90054-w

PGD-M(133161-96-3)Related Product Information

• 4-OXOOCTANOIC ACID
• 4-Ketoundecanoicacid
• 4-OXONONANOIC ACID
• PGD-M