(E)-4-Hydroxy-N-desmethyl Tamoxifen
(E)-4-Hydroxy-N-desmethyl Tamoxifen Basic information
- Product Name:
- (E)-4-Hydroxy-N-desmethyl Tamoxifen
- Synonyms:
-
- (E)-4-Hydroxy-N-desmethyl Tamoxifen
- Tamoxifen 4-Hydroxy N-Desmethyl trans-Isomer
- Phenol, 4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
- Tamoxifen Citrate Impurity 25
- Endoxifen (E-isomer),Inhibitor,Endoxifen (Eisomer),Estrogen Receptor/ERR,Endoxifen (E isomer),inhibit
- CAS:
- 114828-90-9
- MF:
- C25H27NO2
- MW:
- 373.49
- Product Categories:
-
- Aromatics
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 114828-90-9.mol
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(E)-4-Hydroxy-N-desmethyl Tamoxifen Chemical Properties
- Melting point:
- 154-156°C
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White
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(E)-4-Hydroxy-N-desmethyl Tamoxifen Usage And Synthesis
Chemical Properties
White Solid
Uses
A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
(E)-4-Hydroxy-N-desmethyl TamoxifenSupplier
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(E)-4-Hydroxy-N-desmethyl Tamoxifen(114828-90-9)Related Product Information
- (E/Z)-Tamoxifen
- N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
- Tamoxifen Impurity 3
- 4-Benzyloxy β-Hydroxy TaMoxifen
- TaMoxifen DiMer
- 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone
- N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture)
- 4Hydroxy Tamoxifen
- Tamoxifen EP Impurity D
- (E)-4-Alloxycarboxyl Tamoxifen
- Endoxifen
- desdimethyltamoxifen
- TAMOXIFEN-N-OXIDE
- Droloxifene
- (E)-4-Acetoxy Tamoxifen
- N-Desmethyl Tamoxifen Methanethiosulfonate
- 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine
- alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol