Basic information Safety Supplier Related

(E)-4-Hydroxy-N-desmethyl Tamoxifen

Basic information Safety Supplier Related

(E)-4-Hydroxy-N-desmethyl Tamoxifen Basic information

Product Name:
(E)-4-Hydroxy-N-desmethyl Tamoxifen
Synonyms:
  • (E)-4-Hydroxy-N-desmethyl Tamoxifen
  • Tamoxifen 4-Hydroxy N-Desmethyl trans-Isomer
  • Phenol, 4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
  • Tamoxifen Citrate Impurity 25
  • Endoxifen (E-isomer),Inhibitor,Endoxifen (Eisomer),Estrogen Receptor/ERR,Endoxifen (E isomer),inhibit
CAS:
114828-90-9
MF:
C25H27NO2
MW:
373.49
Product Categories:
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
114828-90-9.mol
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(E)-4-Hydroxy-N-desmethyl Tamoxifen Chemical Properties

Melting point:
154-156°C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White
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(E)-4-Hydroxy-N-desmethyl Tamoxifen Usage And Synthesis

Chemical Properties

White Solid

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

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