Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Chemical Properties

Melting point:

104-109 °C (lit.)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

Powder

color 

Yellow

Water Solubility 

Soluble in water.

InChI

InChI=1S/C5H12FN2.F6P/c1-7(2)5(6)8(3)4;1-7(2,3,4,5)6/h1-4H3;/q+1;-1

InChIKey

ZAVXOOLKAGPJPI-UHFFFAOYSA-N

SMILES

C(/F)(=[N+](\C)/C)\N(C)C.[P-](F)(F)(F)(F)(F)F

CAS DataBase Reference

164298-23-1(CAS DataBase Reference)

EPA Substance Registry System

Methanaminium, N-[(dimethylamino)fluoromethylene]-N-methyl-, hexafluorophosphate(1-) (1:1) (164298-23-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

3-10-21

HS Code 

29252900

Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Usage And Synthesis

Chemical Properties

White to off-white powder or crystal

Uses

Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate is used as a reagent for synthesis of cationic antimicrobial β-2,2-amino acid derivatives, philanthotoxin analogues for inhibition of the ionotropic glutamate receptor, small β-peptidomimetics for antimicrobials and hydrazone ligation to assemble multifunctional viral nanoparticles.

Uses

N,N,N',N'-Tetramethylfluoroformamidinium hexafluorophosphate is a useful reagent for in situ conversion of carboxylic acids to acid fluorides. Particularly useful for the coupling of sterically hindered amino acids.

reaction suitability

reaction type: Coupling Reactions

Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate(164298-23-1)Related Product Information

• Chlorfluazuron
• 1,1,3,3-Tetramethylurea
• 3-Dimethylaminopropylamine
• Hexaflumuron
• Lithium hexafluorophosphate
• Tetrabutylammonium hydrogen sulfate
• N,N'-Diisopropylcarbodiimide
• 1-Hydroxybenzotriazole
• HBTU
• 1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE METHIODIDE
• HATU
• N,N,N',N'-Tetramethylethylenediamine
• Tetrabutylammonium bromide
• 2,2,6,6-Tetramethyl-4-piperidinol
• Tetrabutyl ammonium chloride
• Tetrabutylammonium phosphate
• METHYL TETRAHYDROPYRAN-3-CARBOXYLATE
• Fluorine